Outside The Wetlands And The Microorganisms In The Air And Its Effect On The Rat Model

Objective: Humans are tied to nature, and there is in nature an essential condition for people to live. Changes in nature, therefore, may directly or indirectly influence the body, and according cause physiological or pathological reactions. Traditional Chinese Medicine (TCM) think, factors that cause disharmony of the relative balance and lead to disease are the causes of disease, or are known as pathogenic factors. Dampness of six evils is an important factor and condition of invasion to cause common encountered diseases. "Huangdi's Classic of Internal Medicine" is very plentiful about the explanation to dampness. It gave a complete and systematic explanation to the formation factors, quality, position, the clinical manifestations and treatment. These experiments discussion the correlation of the mechanism of external dampness and microorganism. The pathological foundation and rule of external dampness were researched in order to proved pathogenic mechanism of dampness and to create new research method and way in addition to traditional method, promotion of TCM theory to be more scientific and objective, and enable etiology of modern medicine to bring new ideasl and development.Methods: Review the explanation of dampness in"Huangdi's Classic of Internal Medicine" and simply state the concept, formation factors, properties, progress of disease, pathogenic mechanism and symptoms of it in theory, supply a train of thought for experiments and establish the theory foundation. Under the direction of dampness theory and in earlier period experiment foundation, uses the artificial climate box to simulate different natural environment. Healthy rat were divided into seven groups such as external dampness, cold-wetness, heat-wetness, cold, heat, normal and aseptic (relatively aseptic) and so on in the environment makes mold for thirty day. In this foundation, examines corresponding environment the air microorganism, the model rats intestinal tract microorganism and its the adherency situation. At the same time, through the examination immunity function, the gastrointestinal hormone and renal water channel aquaporin, comprehensivly analyze the model animal changes of organism function.Results: In making mold period, the model rats appear the varying degree symptom is because creating the unusual humidity and the temperature. In the certain scope, the majority of Staphylococcus aureus, streptococcus, Legionella pneumophila, Escherichia coli and Eumycetes, increase along with the humidity rise, namely is easier to survival and reproduction under the high humidity environment. In the high humidity environment, the model rats appear the dysbacteriosis in intestinal tract. The number of Escherichia coli increased and the number of Bifidobacterium decreased. This kind of dysbacteriosis has relate to the adhesive effect of the bacteria. The pathogenic bacterium may lead to sick to organism. High humidity also may cause the organism immunity function disorder and the gastrointestinal hormone out of balance. If consider the air microorganism do not...