The Research Of Chinese Medical Ancient Literature About Dispersion-thirst And The Analysis With The Bupleurum Class Treatment Information Nearly 30 Years

The dispersion-thirst disease (Xiao Ke Bing) is a kind of disease name in (TCM), which main clinical manifestations always is more drinking, more food, more urine, weight loss, or Urine turbid, sweet urine and so on. Traditional Chinese Medicine physicians of modern society account diabetes mellitus as dispersion-thirst disease. The incidence of diabetes mellitus is increasing both in developed and developing countries in modern society, and has affected the quality of people life. Diabetes is a lifelong disease, the kinds of complications, morbidity, mortality and health hazards let it ranked the world's No.3 on the overall level non-communicable diseases, therefore, the world pay more attention on the research and treatment of this disease.Traditional Chinese Medicine is an important branch of medicine in the world, which has its own theoretical system and complete knowledge structure. Traditional Chinese medicine has made an indelible contribution to safeguard people's health as a major force in the development of the Chinese nation for thousands of years. The earliest records about dispersion-thirst disease are in Huangdi's Canon of Medicine which elaborate etiology, pathogenesis, mass change, treatment and prognosis of this disease, has laid a solid foundation for the later research. Physicians after the Han Dynasty have developed the etiology, pathogenesis of dispersion-thirst greatly.ObjectiveThis paper summarizes the name meaning of disease, pathogenesis, treatment and other aspects of diabetes from the ancient physicians by sorting the ancient TCM literature.has changed between past and present clinical circumstances due to historical reason, in this case, re-examine the pathogenesis of the dispersion-thirst disease has become very necessary in order to meet the needs of the new era clinical.the dispersion-thirst disease generally belong to the unusual gasification of body fluid, and the San Jiao play a important role in body fluid metabolism, and Bupleurum class prescription is the most appropriate medicine for treating the unusual of the San Jiao. This paper also collect materials of treating diabetes with the Bupleurum class prescription through nearly 30 years, to explore its mechanisms of efficacy and application and demonstrate the adverse of San Jiao is one of an important pathogenesis in diabetes mellitus, therefore, this found may provide an idea and clue to diabetes clinical research and treatment.MethodsThis paper use traditional literature research methods, compiled the ancient literature about dispersion-thirst disease and the materials of treating diabetes with Bupleurum class prescription past 30 years systematically, integrating relevant content, extracting standardized data, summarizing the research of ancient physicians to the dispersion-thirst disease. Use Microsoft Excel and statistical software to analyze the Application of Bupleurum class prescription in the diabetes and its complications clinical.ResultThe study of TCM ancient literature review shows that most of the ancient physicians consider the cause of the dispersion-thirst disease main include improper diet,extreme changes of emotions,attacked by six climate pathogenic factors or toxin,eat more warm dry Dan Stone. Its pathogenesis has consumption of fluid transforming into dryness,the body fluid distribution because weakness, Jue Yin disorders, phlegm and stasis combined together. Many ancient Chinese book is also recorded that the dispersion-thirst disease can occur merger symptoms, including heart disease, kidney disease, eye disease, appendicitis disease, impotence diseases and so on. TCM ancient literature also record that the treatments have nourishing yin to reduce fire, warming and nourishing the kidney, drying dampness and resolving phlegm, invigorating qi and strengthening the spleen, eliminating stasis and promoting blood circulation. In 278 articles about the treatment of diabetes and complications by using Bupleurum class prescription nearly 30 years, there has theoretical exploration, experience cases and clinical observations, animal experiments and so on, the scope of the study involved 28 kinds species of diabetes and its complications. In these articles, randomized controlled clinical research has focused on the past 10 years, and through Jadad scale evaluation and analysis, the overall quality is not high.In the literature included in the study, Xiao Yao San is the most studied prescription, and which also has the most treatment scope; in the clinical study, diabetes of type 2 is the most studied illness; in the same disease, the use of Bupleurum formula is different frequency, such as Chai Hu Shu Gan San is the most studied at diabetic gastroparesis; Xiao Chai Hu Tang is the most studied at diabetic nephropathy.ComclusionThe results show that clinical study about using Bupleurum class to treat diabetes and its complications increasing year by year. The Bupleurum class formula is based on Xiao Chai Hu Tang and Si Ni San, they also have effect of activating qi, balance of yin and yang, smooth activity of blood,San Jiao adverse treatment.San Jiao is the traffic of human body, which Connect the outside and inside aspects from top to bottom, San Jiao also is the channel of Yuan-qi, and can regulate water metabolism. Under normal circumstances,San Jiao coordinate the internal organs function and order of fluid metabolism, chemical and biological substances, transmission distribution, infiltration, drainage and other physical activities can be carried out normally. If San Jiao road congestion, qi is blocked, the water fluid, subtle material conversion, transport will be disorder, gas, blood, fluid, fluid does not reformed, On the contrary, phlegm, dampness, blood stasis are produced, so the diabetes symptoms of dry mouth, thirst, appetite, urination increase, body weight loss may occur.The changes of increasing or decreasing based on Bupleurum class prescription, make applied methods multiple. Bupleurum class prescription ease San Jiao stagnation, smooth San Jiao roads, let San Jiao rousing, and its gasification back to normal, the body fluid metabolism in order, blood with qi and the yin with yang reach equilibrium. Bupleurum class prescription apply at the clinical treatment should based on syndrome, Bupleurum class prescription is the basis part treatment for the dispersion-thirst disease, its application in the organs dysfunction, viscera asthenia is the Contraindications of Bupleurum class prescription.