The Exploration Of Clinical Experience For Professor Liu Wen-feng In Treating Dispersion-thirst Disease With Eye Disease

Research purposes:To study the experience and clinical thought of the ancient Chinese medicine doctor and famous old doctor professor liu wenfeng in the treatment of dispersion-thirst disease with eye disease.and provide a new treatment idea and method for the clinical diagnosis and treatment of dispersion-thirst disease with eye disease.Research method:1.Through the research of literature and data,this paper reviews the cognition and treatment of traditional Chinese medicine(TCM)doctors in the past dynasties,and summarizes their academic thoughts and experiences.2.On the basis of TCM inheritance auxiliary platform 2.5,a database was established for the 327 prescriptions of various doctors in the past 10 years for the treatment of dispersion-thirst disease with eye disease.Data mining was carried out on the medicines,drugs,properties,tastes and meridians of traditional Chinese medicine in the prescription.Frequency analysis,frequency analysis and correlation analysis were used to summarize the medication rules of traditional Chinese medicine prescriptions for the treatment of dispersion-thirst disease with eye disease in recent years,and new formulations were excavated and explored in combination with clinical pharmacology.3.Summarize the academic thoughts of professor liu wenfeng on the treatment of dispersion-thirst disease with eye disease,and analyze the self-designed qizi mingmu decoction,and combine the results of modern pharmacological research to refine the uniqueness of Professor Liu Wenfeng on the treatment of dispersion-thirst disease with eye disease.Research result:1.Due to the constraints of historical conditions,historical doctors have limited records of the treatment of dispersion-thirst disease with eye disease.Through a great deal of literature reading and investigation of ancient books,It can be seen that dispersion-thirst disease with dispersion-thirst disease with eye disease and diabetes belong to the relationship between partand whole,stage and whole process.with the deepening of the cognition and the change of the treatment methods of the diabetes,the understanding of the pathogenesis of the dispersion-thirst disease with eye disease also has distinctive characteristics of The Times and its own unique features.From the period of The Inner Canon of Huangdi to the Ming and Qing Dynasties,there were doctors who continuously studied and discussed the diabetes and dispersion-thirst disease with eye disease elimination.The cognition and treatment thoughts of dispersion-thirst disease with eye disease were also changed from the discussion of the etiology and pathogenesis of the disease to the specific treatment ideas and guidance methods.It can be seen that for thousands of years,countless Chinese medical experts have not stopped the pursuit of the diagnosis and treatment of dispersion-thirst disease with eye disease,which is also an important impetus for traditional Chinese medicine to maintain vitality.2.Based on the auxiliary platform of traditional Chinese medicine inheritance,data mining was carried out on 327 prescriptions,involving 258 traditional Chinese medicines,for the treatment of dispersion-thirst disease with eye disease in recent 10 years.Occurrence frequency is highest is astragalus membranaceus,salvia miltiorrhiza,lycium barbarum,poria cocos,atractylodes macrocephala,alisma orientale,high-frequency drugs by replenishing qi and nourishing yin,promoting blood circulation and removing blood stasis,invigorating spleen to remove dampness,tonifying the liver and kidney is the main component of astragalus membranaceus are most frequently appear in the medicine,overall core drug by activating blood circulation and removing blood stasis and activating meridians,Tonifying qi,blood,liver and kidney,eliminating dampness and detoxicant,dispersing stagnated liver qi to relieve depression,improving eyesight.The correlation analysis of 258 traditional Chinese medicines in 327 prescriptions showed that the 18 pairs with the highest frequency of occurrence were obtained.Respectively:salvia miltiorrhiza and astragalus membranaceus,lycium barbarum and astragalus membranaceus,salvia miltiorrhiza and lycium barbarum,atractylodes macrocephala and poria cocos,salvia miltiorrhiza and poria cocos,salvia miltiorrhiza and epimedium,salvia miltiorrhiza and lycopus lucidus turcz,poria cocos andlycium barbarum,poria cocos and astragalus membranaceus,alisma orientale and poria cocos,salvia miltiorrhiza and alisma orientale,salvia miltiorrhiza and atractylodes macrocephala,lycopus lucidus turcz andastragalus membranaceus,Rosa laevigata Michx fruit and lycium barbarum,lycium barbarum and epimedium,atractylodes macrocephala and astragalus membranaceus,poria cocos and epimedium,alisma orientale and lycium barbarum.Based on improved mutual information method of correlation coefficient between drug medicine for 17 is greater than 0.1,respectively:chrysanthemum indicum and shepherd's-purse,chrysanthemum indicum and lycium barbarum,rosa laevigata Michx fruit and alisma orientale,epimedium and poria cocos,rosa laevigata Michx fruit and shepherd's-purse,lycopus lucidus turcz and Euryale ferox Salisb,chrysanthemum indicumand atract ylodes macrocephala,Euryale ferox Salisb and epimedium,epimedium and atractylodes macrocephala,alisma orientale and lycium barbarum,Leonurus japonicus and atractylodes macrocephala,alisma orientale and atractylodes macrocephala,lycopus lucidus turcz and shepherd's-purse,Leonurus japonicus and lycium barbarum,Rosa laevigata Michx fruit and poria cocos,chrysanthemum indicum and Rheum palmatum,Leonurus japonicus and poria cocos.Based on complex entropy clustering,14 core combinations of 3?5 herbs were derived,which were scorpion:scorpion,Vitex rotundifolia,Angelica Dahurica;Uncaria rhynchophylla,Prunella Vulgaris,Evodia rutaecarpa;Citrus aurantium,Bupleurum chinense,Platycodon grandiflorum;Coix lacryma-jobi,Polygonatum ordoratum,Spatholobus suberectus Dunn;Ziziphus jujuba,polygala,Schisandra chinensis;Pinellia ternata,Citrus reticulata Blanco,Magnolia officinalis;Psoralea corylifolia,ground beetle,rhizoma Drynariae,Phryma leptostachya;scorpion,Bombyxmori Linnaeus,Typhonium giganteum;Uncaria rhynchophylla,Prunella Vulgaris,fry Tribulus terrestris;Citrus aurantium,semen pruni,Magnolia officinalis;Coix lacryma-jobi,Eupatorium fortunei,silkworm excrement;Ziziphus jujuba,Schisandra chinensis,Lilium;semen pruni,Citrus reticulata Blanco,Magnolia officinalis;Polygonum cuspidatum,Centella asiatica,ground beetle,rhizoma Drynariae,Cistanche desertico La.Derived 7 new recipe,respectively:scorpion,Vitex rotundifolia,Angelica Dahurica,Bombyxmori Linnaeus,Typhonium giganteum;Uncaria rhynchophylla,Prunella Vulgaris,Evodia rutaecarpa,fry Tribulus terrestris;Citrus aurantium,Bupleurum chinense,Platycodon grandiflorum,semen pruni,Magnolia officinalis;Coix lacryma-jobi,Polygonatum ordoratum,Spatholobus suberectus Dunn,Eupatorium fortunei,silkworm excrement;Ziziphus jujuba,Polygala,Schisandra chinensis,Lilium;Pinellia ternata,Citrus reticulata Blanco,Magnolia officinalis,semen pruni;Psoralea corylifolia,ground beetle,rhizoma Drynariae,Phryma leptostachya,Polygonum cuspidatum,Centella asiatica,Cistanche desertico La.3.Professor liu wenfeng summarized the basic etiology and pathogenesis of dispersion-thirst disease with eye disease:qi deficiency and blood stasis,phlegm-wet internal resistance,deficiency of liver-yin and kidney-yin,liver depression and heat generation,blood-heat bleeding and so on.Among them,the deficiency is the basis,and the stasis is the standard,Many pathological factors intermingle and interact with each other.Professor liu thinks any illness of an era has its distinct characteristics of The Times,even if is roughly similar disease,due to the sick body is affected by the different social environment,era background,its pathogenesis is not the same,also on the treatment should be flexible,according to different pathogenesis of different treatment options,we should try to be the ancient while not old.Considering that the current social people's living pressure,work pressure and environmental changes have very distinct characteristics than any previous era,professor liu paid more attention to the liver depression in the treatment of dispersion-thirst disease with eye disease.In the traditional theory of traditional Chinese medicine,the liver is connected to the eye,the liver is connected to the meridian of the eye,the liver collects blood,so the eye receives blood and can see,the liver qi is connected to the eye,the liver qi can reach the eye,and the Yin and Yang are harmonized,the eye can see.In the theory of“General Treatise on the Cause and Symptoms of Diseases”,it is said that“the disease of internal obstruction is serious,the deficiency and decline of zang-fu organs”,and in the theory of“secret yanke longmu lun”(???????),it is said that"the kidney is poisoned by wind,so the liver is deficient",which is a high summary of the pathogenesis of liver and quenching thirst,and the purpose of physiological and pathological status is closely related.Therefore,in the course of clinical syndrome differentiation and treatment of dispersion-thirst disease with eye disease,professor liu focuses on the treatment of liver stagnation,in the treatment process to advocate the patients'good mood,maintain a happy mood,reduce the negative emotional impact of eye disease to patients.According to qi zi Ming mu decoction,syndrome differentiation and treatment of the disease.Conclusion:Since“the Inner Canon of Huangdi” period,Chinese medical practitioners have begun to discuss and attempt the treatment of diabetes and dispersion-thirst disease with eye disease.After thousands of years of efforts,Chinese medical practitioners have reached an unprecedented height in the theoretical treatment of the dispersion-thirst disease with eye disease.Our need for medical treatment and science and technology has promoted the continuous improvement of the level of science and technology and medical treatment.Human beings have never stopped pursuing the pace of medicine,traditional Chinese medicine has been constantly changing and evolving in this magnificent trend of the times,reaching a height never touched by the ancient people.In recent years,with the progress of medical technology and the rapid development of diagnosis and treatment methods,people's research on the internal material level,pathophysiological reaction and cytokines of dispersion-thirst disease with eye disease has been further deepened,and the research on Chinese medicine ingredients and the level of clinical application has been further improved,and the treatment of dispersion-thirst disease with eye disease has become more diversified.Based on the auxiliary platform of traditional Chinese medicine inheritance,data mining was conducted on 327 prescriptions used in clinical treatment of dispersion-thirst disease with eye disease in recent 10 years.It was found that the modern medical practitioners mainly treated thedispersion-thirst disease with eye disease by replenishing qi and nourishing Yin,promoting blood circulation and removing blood stasis,strengthening spleen and kidney,and dispelling dampness and promotinging diuresis.and many have never seen in the history of literature is used to treat diabetes,dispersion-thirst disease with eye disease and even drugs also appear in the present applications of collateral,shows the study of modern Chinese medicine pharmacology is in progress.At the same time,based on the entropy clustering analysis,we can get a new treatment for anemone disease,which also provides us with more possibilities and directions for the treatment of anemone disease in the future.Professor liu wenfeng has been engaged in the medical treatment of traditional Chinese medicine for more than 50 years,especially in the treatment of diabetes and diabetic complications.This paper summarizes in detail professor liu wenfeng's academic thought and clinical experience from the aspects of etiology,pathogenesis,treatment principle and prescription.It reflects his thought of "taking part in the west" and provides a great referencevalue for the treatment of dispersion-thirst disease with eye disease.