Diagnostic Standard Study Of Damp-heat In The Spleen-stomach Syndrome And Primary Exploration Of "Measure Syndrome By Drug" Method

Object: The theory of syndrome is the connection part from theory to clinical practice in traditional Chinese medicine system, the significance is self-evident To study T.C.M. theory of syndrome, the primary task is to define the meaning of syndrome dearly. Otherwise the study cannot be carry out, even if carry out. the conclusion is hard of reauthenticafon. and cannot be deployed. The "syndrome" of T.C.M. is more than just description of external sign and symptom group, it is also the summarization of reaction to specific T.C.M. drugs. As a result that the concept of pathogenesis, degree of seriousness of illness in T.C.M. is much more abstract than modem medical theory, the influence of clinical practice is much more important to T.C.M. syndrome than modem medicine. In T.C.M.. there is no "gold standard" of diagnosing syndrome or symptom complex that was independent to medical treatment procedural, so there has no means of establishing clinical diagnosis standard by compare with "gold standard" To define T.C.M. syndrome clearly, we should comprehend the discuss of predecessor, we should also master it's reaction to specific T.C.M. medicine. First of all. diagnostic criteria of T.C.M. syndrome should meet the literature in the past. Secondly, it should effective when applied in practice. Thirdly, the standard itself should plain and terse. The main object of this article is in search of a proper diagnostic stander of damp-heat in the spleen-stomach syndrome. At the same time, we would like to discuss the method of "measure syndrome with drug" in syndrome standard study. The purpose of introducing this method is to try solving the insoluble "gold standard" issue in T.C.M. diagnostics study.Method: In this study, first we will discuss the academic source of diagnosing and treating damp-heat in the spleen-stomach syndrome. Then we went on a questionnaire survey of diagnosing damp-heat in the spleen-stomach syndrome in specialist around the state. And then there is a statistic on discusses of medical publication that involved diagnose of damp-heat in the spleen-stomach syndrome and other dampheat syndromes. Clinical research is in two parts. Part one is a clinical investigation of diagnostic standard according to formerly described study mode. The population of survey is the inpatient of the No.2 department of internal medicine and outpatient of outpatient service department of internal medicine of the 1st affiliated hospital of our university. Diagnostic standard of observation object is the damp-heat in the spleen-stomach syndrome diagnostic standard described in Chinese traditional medicine new drug clinical research guiding principle and / or the diagnostic standard made by our department. Diagnostic standard of other syndrome is those described in Chinese traditional medicine new drug clinical research guiding principle. The observation item is obtained in literature study. Sign and diagnose of Western medicine and T.C.M. is recorded. The signs that is hard to judge such as type of the tongue, type of pulse, is verified by experienced physician. To some cases that failed to meet diagnostic standard, but diagnosed a certain syndrome by physician, the physician's diagnose is supported, in case of missing valuable sign. Chi-square test is performed to pick up sign and symptom with significance after certain quantity of case is entered. Logistic regression analysis is performed to get discriminant function. Grouping is performedwith discriminant function when new cases added, and the effectiveness of grouping is compared with the original diagnostic standard. Treatment study is performed with the patients diagnosed damp-heat in the spleen-stomach syndrome, to discuss the method of "measure syndrome with drug". The therapy is the SanRen recipe. Radix scutellariae, calamus, turmeric hairy china cardamoms, dried old orange peel is added to the recipes. Disappearances of subjective symptom like appetite, mental state and taste is taken as criterion of therapeutical effect. Some objective symptom like halitosis,...