Effect Of Xuesaitong Dropping Pill Combined With Acupuncture And Moxibustion And Massage On Clinical Symptoms And Hemodynamics Of Cervical Spondylosis With Qi Stagnation And Blood Stasis Syndrome

Objective:In this study,taking advantage of the effects of xuesaitong preparation on activating blood circulation,removing blood stasis,detumescence and pain,and promoting blood circulation,while implementing acupuncture and moxibustion and massage for cervical spondylosis patients with qi stagnation and blood stasis syndrome,xuesaitong preparation with the function of guiding channels and unblocking collaterals was given to observe the effect of xuesaitong preparation combined with acupuncture and moxibustion and massage on the clinical symptoms and hemodynamics of cervical spondylosis with xuesaitong and blood stasis syndrome.Methods:The subjects were randomly divided into two groups.The control group was treated with acupuncture and moxibustion and massage once a day for 10 days;The experimental group was treated with Sanqi preparation combined with acupuncture and moxibustion and massage,taking Xuesaitong dropping pills,20 pills each time,3 times a day,for 10 consecutive days in combination with acupuncture and moxibustion.The two groups of patients have the same acupoint selection and operation time,and 10 days is a course of treatment.The Visual Analogue Scale(VAS),Northwick Park Questionnaire(NPQ),Neck Disability Index(NDI),and hemodynamic parameters were compared between the two groups before and after treatment.The two groups of patients were followed up at the first,third,and sixth months after discharge.The follow-up results were compared with those before and after treatment,and the results of follow-up at different periods were compared(inter group and intra group comparisons).Results:1.88 patients enrolled,42 cases in the control group,46 cases in the experimental group.2.Baseline results.The general information(including gender,age,occupation,etc.),visual analogue score(VAS),cervical pain scale(NPQ),and cervical dysfunction index(NDI)of the two groups of patients were compared,and the differences were not statistically significant(p>0.05),which was comparable;There were significant differences in right vertebral artery blood flow velocity,basilar artery pulsation index,impedance index,and peak to valley ratio of blood flow velocity(p<0.05),which were not comparable;The other hemodynamic parameters have no significant difference(p>0.05)and are comparable.3.Clinical symptoms after treatment.After treatment,the total scores and dimensions of VAS scale,NPQ scale,and NDI scale in the two groups were significantly different from those before treatment(p<0.05).The total scores of NPQ and NDI scales in the experimental group were significantly different from those in the control group(p<0.05);In the NPQ scale,there were significant differences in the scores of the three dimensions of "feeling numbness or acupuncture in the arm at night","daily symptom duration",and "reading and watching TV" compared to the control group(p<0.05).4.Hemodynamics after treatment.Intragroup comparison:The blood flow velocity of the right vertebral artery in the control group was significantly different from that before treatment(p<0.05);In the experimental group,the blood flow velocity of the basilar artery and the diastolic blood flow velocity of the left conical artery were significantly different from those before treatment(p<0.05).Comparison between groups:The blood flow velocities of the basilar artery and the left pyramidal artery,the pulsation index of the left pyramidal artery,and the peak to valley blood flow velocity in the experimental group were significantly different from those in the control group(p<0.05).5.Efficacy evaluation.The total effective rate of both groups was 100%,and the number of significantly effective cases in the experimental group(43 cases)was significantly higher than that in the control group(29 cases).The significant recovery rates were 69.05%and 93.48%,respectively,with a significant difference(p=0.003,p<0.05).6.Follow up results.Compared with before treatment,there were significant differences in VAS,NPQ,and NDI scores between the two groups at the first,third,and sixth month follow-up after discharge(p<0.05).The NPQ scale scores at the third month follow-up after discharge in the test group were lower than those after treatment(p=0.039<0.05).Conclusion:Sanqi preparation combined with acupuncture and moxibustion and massage can effectively improve the clinical symptoms of cervical spondylosis patients with qi stagnation and blood stasis syndrome,improve their blood flow speed,and its clinical effect and stability of efficacy are better than that of acupuncture and moxibustion and massage alone.