Shuxuetong Injection In Treatment Of Different Syndromes Of Acute Cerebral Infarction And Clinical Observation,

ObjectiveIschemic stroke(cerebral infarction)is one of the internal medicine of common diseases,a high incidence rate and high morbidity characteristics.Many patients survived after treatment in different degrees of neurological deficit,to the family and the community a heavy financial burden.This study was observed Shuxuetong treatment of acute phase of clinical efficacy and safety of on Shuxuetong in the acute phase of treatment of different cards on the application.Method1.All cases of clinical data in December 2006 to December 2007 the Department of Neurology,patients of Chinese medicine hospitals in Hubei Province,a total of 80 patients were randomly divided into treatment and control groups,including the treatment group of 40 cases,40 cases of the control group.The two groups in age,sex,disease,stroke and treatment before the disease score,neurological impairment integration, integration of Chinese medicine syndrome,the main symptoms of Chinese medicine evaluation score,with points of the disease,previous history score,the statistical analysis,no significant Differences(P＞0.05), are comparable.2.Drug use in treatment group:Shuxuetong injection.Control group: Ciwujia injection.The treatment group give Shuxuetong injection 6mlto 5%glucose solution 250ml,or 0.9 percent sodium chloride solution 250 ml infusion day one,sharing of 14 days;the control group give Ciwujia 250ml intravenous injection on day one,Sharing of 14 days.The course of treatment using two cases were related to therapy and symptomatic treatment.3.Efficacy and safety of the two groups observed that the newly diagnosed patients before and after treatment and medication after 14 days of observation to make a record,to be in effect for stroke patients,the nerve function score,TCM Syndrome,signs score,before and after treatment for fecal conventional hematuria,Liver and kidney function (ALT,AST,BUN,Cr),electrocardiogram test,skull CT and to observe whether patients with spontaneous stasis,Yuban,and then,such as bleeding tendency.4.Statistical count information with the X~2 test,measurement data used t-test,grading information with the Ridit test.Results1.Effects of a stroke:the treatment group cured four cases,markedly effective in 18 cases,progress in 10 cases,eight cases invalid,and the total efficiency of 80.0 percent;control group cured three cases,15 cases markedly effective,and progress in 11 cases,11 cases of invalid, And the total efficiency of 72.5 percent.Through statistical analysis, there were no significant differences in the efficiency of significance (P＞0.05).Note Shuxuetong injection and Ciwujia injection of two drugs on the stroke symptoms improved significantly for the role.2.Syndrome effects of Chinese medicine:the treatment group cured three cases,markedly effective in 19 cases,progress in 10 cases,eight cases invalid,and the total efficiency of 80.0 percent;control group cured two cases,markedly effective in 16 cases,13 cases of progress, invalid 9 Cases,the total efficiency of 77.5 percent.Through statistical analysis,there were no significant differences in the efficiency of significance(P＞0.05).Note Shuxuetong injection and Ciwujia injection of two drugs on the stroke of Chinese medicine syndrome have significantly improved efficacy.3.The degree of neurological deficit effects:the treatment group cured four cases,markedly effective in 19 cases,progress in 10 cases, no change in seven cases,the total efficiency of 82.5%;the control group cured three cases,markedly effective in 17 cases,12 cases of progress, No change in eight cases,the total efficiency of 80.0 percent.Through statistical analysis,there were no significant differences in the efficiency of significance(P＞0.05),that Shuxuetong injection and Ciwujia injection of two drugs on the stroke of neurological deficits significantly improve the efficacy.4.TCM different card type of neurological impairment effects:the treatment group:Wind sputum into meridian-cured 0 case,markedly effective five cases,five cases of progress,no change in three cases, the total efficiency of 76.9 percent;Wind-yang nuisance-cured three cases,ten cases markedly effective,progressive one case,one case of no change,the total efficiency of 93.3 percent;Yin pneumatic-cured one cases,four cases markedly effective,progressive four cases,no change in three cases,the 75.0%efficient,the control group:Wind sputum into meridian-cured 0 cases,four cases markedly effective,progressive six cases,no change in four cases,the total efficiency of 71.4 percent; Wind-Yang nuisance-cured type 1 cases,three cases markedly effective, Progressive six cases,no change in three cases,the total efficiency of 71.4 percent;Yin pneumatic-cured two cases,ten cases markedly effective, progressive 0 case,one case of no change,the total efficiency of 92.3 percent.The treatment group and control group on the Wind-Yang nuisance of the total efficiency of more significant difference(P＜0.05),that Shuxuetong injection on Wind-Yang nuisance-on effect is better than cerebral infarction Ciwujia injection;in the control group and the treatment group Yin pneumatic total efficiency of more significant difference(P＜0.05),that Ciwujia injection on Yin pneumatic-effective than cerebral infarction Shuxuetong injection;the treatment group into Wind sputum into meridian and the type of Yin pneumatic-efficient no significant difference(P＞0.05),Wind-Yang nuisance and Wind sputum into meridian and Yin pneumatic total efficiency of more significant difference(P＜0.05),That Shuxuetong injection on Wind-Yang nuisance of cerebral infarction-effective than other type of cerebral infarction;the control group Wind sputum into meridian and Wind-Yang nuisance on the total efficiency no significant difference(P＞0.05), Yin pneumatic-and Wind-Yang nuisance-and Wind sputum into meridian on the total efficiency of more significant difference(P＜0.05),Ciwujia that the Yin pneumatic-effective than other cerebral infarction Cerebral infarction.5.Adverse reactions and side effects:the treatment group and control group in the clinical observation period,no apparent adverse reactions and side effects.Laboratory results of the two groups(three conventional, liver and kidney function,ECG,skull CT)were not there before and after treatment and treatment related to abnormal changes and have not found a spontaneous stasis,Yuban,and then,such as bleeding tendencies.Conclusion:The results showed that observation:Shuxuetong injection in the treatment group and Ciwujia injection in the control group of stroke patients found integral effect,neurological deficits,TCM Syndrome points,the statistical analysis showed no significant difference.They can reduce disability and reduce disability,increase the quality of life and clinical application of safe and effective.Shuxuetong injection in the treatment of acute cerebral infarction(Wind-Yang nuisance)a better efficacy in the treatment of cerebral infarction should Differential Treatment.