Clinical Observation On Puzhixiangshaliujunzi Decoction In The Treatment Of Spleen Deficiency And Dampness Stagnation Syndrome After Laparoscopic Colorectal Cancer Surger

Objective: The purpose of this research is to explore the clinical efficacy of Pozhi Xiang Sha Six Jun Zi Decoction on the rapid recovery of postoperative colorectal cancer patients and evaluate its safety,in order to provide ideas and theoretical basis for the involvement of Traditional Chinese Medicine in Enhanced recovery after surgery.Methods: From September 2021 to September 2022,68 patients who met the inclusion criteria in the General Surgery Department of the Dianjiang hospital affiliated to Hunan University of Chinese Medicine,were diagnosed with colorectal cancer and underwent laparoscopic radical colorectal cancer surgery,and were randomly divided into 34 each in the control group and the observation group.Both groups received perioperative management of enhanced recovery after surgery.In the observation group,Po Zhi Xiang Sha Six Jun Zi Decoction was administered orally on postoperative day 1 for 7 days.The two groups were compared for statistical analysis of the changes in inflammatory indexes before surgery and on day 1,day 3 and day 7 after surgery,the time of first exhaust,the time of first defecation,degree of abdominal pain,degree of abdominal distension,days of hospitalization,efficacy of recovery of gastrointestinal function,TCM syndrome score and other related factors.Results: 68 cases were included in this research,with 1 dropped out case in control group,2dropped out cases in observation group.The valid cases are 65,with 33 in control group and 32 in observation group.Baseline analysis: There was no statistically significant difference in general information between the two groups(P>0.05),and the baseline was consistent and comparable.Main indicators analysis: The inflammatory indexes of the observation group were lower and decreased faster than those in the control group on the 3rd and 7th day after surgery,and the differences were statistically significant(P<0.05).The time of first exhaust and first defecation in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).The degree of abdominal pain and abdominal distension in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The number of days of hospitalization in the observation group were less than that in the control group,and the differences were statistically significant(P<0.05).The efficacy of gastrointestinal function recovery in the observation group was better than that in the control group,with an effective rate of 96.88% in the observation group and 84.85% in the control group,and the difference was statistically significant(P<0.05).The TCM syndrome score of observation group was significantly lower than the control group.The total effective rate of the observation group was 93.75%,which was significantly higher than that of the control group(81.82%),with statistical significance(P<0.05).Secondary indicators analysis: During the observation period there was no adverse event.There was no significant difference in the incidence of postoperative complications between the observation group and the control group(P>0.05).Conclusion: Po Zhi Xiang Sha Six Jun Zi Decoction can promote the decrease of inflammatory indexes,accelerates the recovery of gastrointestinal function,relieve the abdominal pain and abdominal distension,shorten the hospital stay,without adverse events,without increasing the incidence of postoperative complications,and accelerate the rapid recovery of postoperative patients after colorectal cancer,which can provide a clinical basis for Chinese medicine to promote Enhanced recovery after surgery.