| Objective:The purpose of this study was to observe the clinical efficacy of acupuncture combined with facial sanyang meridian points self-blood therapy in the treatment of chloasma,evaluate the feasibility and practicability of acupuncture combined with self-blood acupoint injection of facial Sanyang meridians in the treatment of chloasma,and provide different ideas and treatment schemes for acupuncture in the treatent of chloasma.Methods:66 patients who met the inclusion criteria were randomly divided into the control group and the treatment group in a 1:1 ratio,with 33 in each group.The control group was treated with acupuncture,and the number of acupoints was increased or decreased according to the syndrome,six a week,with 2 weeks as a course of treatment;The treatment group was treated with acupuncture combined with facial sanyang meridian points self-blood therapy.The acupuncture treatment was the same as that of the control group,The self-blood treatment was carried out after acupuncture,twice a week,Both groups of patients were treated for two consecutive courses of treatment.VISIA image analysis,melasma area and severity index score(MASI),and total score were recorded before and after treatment,satisfaction level of patients and decline index were recorded after treatment,recurrence rate in the sixth month after treatment were recorded,and the overall clinical efficacy was evaluated.Results:A total of 61 cases were completed in this project,including 31 cases in the control group and 30 cases in the treatment group.1.There was no remarkable disparity between the two groups in age,course of disease,MASI score,facial spot score,red spot score,brown spot score,ultraviolet spot score and total score before therapy(P>0.05).2.Comparison of MASI scores in the 2nd and 4th weeks after treatment(1)Comparison between groups:the MASI scores of the control group and the observation group at the 2nd and 4th weeks after treatment were not remarkable disparity(P>0.05);(2)Intra-group comparison:The MASI scores of the control group and the observation group at the 2nd and 4th weeks after treatment were improved compared with before treatment(P<0.05).But,there was little difference in scores between the two groups at week 2 after treatment,The score of the treatment group was slightly lower than the control group at the 4th week after treatment.3.Comparison of satisfaction between the two groups after treatment(1)2 weeks after treatment:the proportion of satisfaction in the observation group was36.70%,and the control group was 22.60%.Satisfaction in the treatment group was higher than in the control group but no significant difference between the two groups through chi-square test(P>0.05).(2)4 weeks after treatment:the proportion of satisfaction in the observation group was53.30%,and the control group was 41.90%.The satisfaction in the observation group was higher than in the control group,and the satisfaction in both groups was higher than that in the second week.After the chi-square test,there was no significant difference between the two groups(P>0.05).4.VISIA image analysis and comparison(1)Facial spots(1)Comparison between groups:there was no significant difference in absolute scores of left spot and middle spot after treatment(P>0.05);The absolute score difference of right facial spot is statistically significant(P<0.05),the curative effect of the treatment group was better than the control group;(2)Intra-group comparison:after treatment,the absolute scores of left and middle facial spots in the treatment group and control group were lower than before treatment,after statistical analys the difference was significant(P<0.05);(3)Comparison of the difference between the two groups:the difference between the left side and the middle side of the face was not statistically important(P>0.05).(2)Face red area(1)Comparison between groups:After treatment,there was no important difference in the absolute score of facial red area(left/middle/right)between the two groups(P>0.05);(2)Intra-group comparison: after treatment,the absolute scores of the left,middle and right facial red areas in the treatment group and the control group were lower than before treatment,and the difference was significant(P<0.05);(3)Comparison of the difference between the two groups:the difference between the left,middle and right red areas of the face was statistically significant(P<0.05).(3)Brown spots on face(1)Comparison between groups:After treatment,there was no important difference in the absolute scores of left,middle and right facial brown spots between the two groups(P>0.05);(2)Intra-group comparison:after treatment,the absolute scores of brown spots on the left,middle and right sides of the face in the treatment group and the control group were lower than before treatment,and the difference was significant(P<0.05);(3)Comparison of the difference between the two groups:the difference of brown spots on the left,middle and right sides of the face was not statistically significant(P>0.05).(4)Facial ultraviolet spots(1)Comparison between groups:After treatment,there was no significant difference in the absolute scores of left,middle and right facial ultraviolet spots between the two groups(P>0.05);(2)Intra-group comparison:after treatment,the absolute scores of the left,middle and right side of the ultraviolet spots in the treatment group and the control group were lower than before treatment,and the difference was significant(P<0.05);(3)Comparison of the difference between the two groups:the difference between the two groups was not significant(P>0.05).5.Comparison of total treatment score and decline indexAfter treatment,the total score of patients with chloasma in both groups decreased,and the degree and index of decline of the total score in the treatment group were slightly higher than those in the control group,but the statistical analysis showed that the total score and index of decline of patients were not statistically significant(P>0.05),which could not explain which group was more superior.6.Comparison of effectiveness between the two groups after treatmentAfter treatment,the total effective rate of the acupuncture group was 67.70%,the control group was 76.70%.The total effective rate of the two groups in the observation group was slightly higher than that in the control group,but there was no significant difference through statistical analysis(P>0.05),indicating that the overall effect of the acupuncture group and the acupuncture combined with self-blood acupoint injection group was equivalent.7.Comparison of recurrence rates between the two groupsAt the follow-up of 6 months after treatment,the control group recurred,accounting for22.60%,and the treatment group recurred,accounting for 16.70%.The recurrence rate in the treatment group was lower than the control group,but the statistical analysis showed that there was no significant difference in the recurrence rate between the two groups(P>0.05).conclusion:1.Treatment group and acupuncture group can improve the MASI score,satisfaction,VISIA absolute score,total score and decline index of patients with chloasma,and there is no obvious adverse reaction.The longer the treatment time,the more obvious the changes in the MASI score and satisfaction of patients in the observation group compared with the control group;2.In terms of the overall effective rate,both groups were effective for chloasma,but the treatment group was slightly higher than the control group;3.The absolute score improvement of left facial spot and facial red area in treatment group was better than that in control group;4.Acupuncture combined with auto-blood point injection can be used as a safe and reliable combined treatment for chloasma,with good curative effect,which is worthy of further study. |
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