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Clinical Study On Treatment Of Type ⅢB Prostatitis With Damp-heat And Stasis Syndrome By Combining With Chinese Herbal Immunomodulators And Clearing Heat Relieving Dampness Promoting Blood Circulation

Posted on:2022-05-02Degree:MasterType:Thesis
Country:ChinaCandidate:Y D ZhangFull Text:PDF
GTID:2504306533956259Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Objective:A clinical study on the treatment of type ⅢB prostatitis(CP)damp-heat stasis syndrome by Chinese medicine immunomodulators combined with method of clearing heat,removing dampness,activating blood and single-use method of clearing heat,removing dampness,activating blood,Observing the TCM scores of damp-heat stasis syndrome,Inflammatory symptom index total score(NIH-CPSI),three factor scores,prostatic fluid(EPS-SPL)status,prostate palpation tenderness and other index changes prior treatment and posttreatment,to evaluate the clinical efficacy of single-use the method of removing heat,removing dampness,activating blood and Chinese medicine immunomodulators combined with the method of clearing heat,removing dampness,activating blood to treat type ⅢB prostatitis with damp-heat stasis syndrome,providing clinical evidence for exploring the treatment of type ⅢB prostatitis with traditional Chinese medicine immunomodulators method:In this study,all the cases were collected from patients in the Urological department of the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine between July 2020 to December 2020.100 cases were enrolled,which met the diagnostic criteria for type IIIB CP and the diagnostic criteria for damp-heat stasis syndrome in traditional Chinese medicine,and were screened by the acceptance criteria.Randomly divided into test group of50 cases,given oral Chinese medicine immunomodulators total glucosides of paeony capsules and method of clearing heat,removing dampness,activating blood Longjin Tonglin capsules,and control group 50 cases,given only oral method of clearing heat,removing dampness,activating blood Longjintonglin capsules,a total of 4 weeks of treatment.TCM syndrome score and chronic prostatitis symptom index score(NIH-CPSI)were scored before treatment,the second week the fourth week after treatment.The clinical symptoms of prostate tenderness,lecithin body count,etc.were recorded before and after treatment,using statistical analysis to evaluate the clinical efficacy of the two groups of patients.result:1.In this study,a total of 100 patients were included,3 cases were dropped,48 cases were completed in the experimental group,and 49 cases were completed in the control group.2.Before treatment,there was no statistically significant difference in the age,marital status,duration of the disease,and previous history of CP between the two groups of patients(P>0.05).3.Before treatment,there was no significant difference in TCM scores of damp-heat stasis syndrome,NIH-CPSI score,prostate palpation tenderness,and EPS-SPL count between the two groups of patients(P>0.05).4.After treatment,the effective rate of the test group was 89.5%,2 cases were cured,14 cases were significantly effective,27 cases were effective,and 5 cases were ineffective;in the control group,the effective rate was 79.5%,0 cases were cured,4 cases were significantly effective,35 cases were effective,and 10 cases were ineffective.The results of rank sum test showed significant differences(P<0.01).5.After treatment,compared with before treatment,the NIH-CPSI score,quality of life,pain and discomfort,and urinary symptom scores of the two groups of patients were lower,and the difference was statistically significant(P<0.01);Compared with the control group,the test group NIH-CPSI score,quality of life,pain and discomfort score,the decrease was more obvious,and the difference was statistically significant(P<0.05);compared with the control group,the test group’s urination symptom score decreased,the difference was not statistically significant(P>0.05).6.After treatment,compared with before treatment,TCM scores of damp-heat stasis syndrome of the two groups of patients were significantly lower(P<0.01);compared with the control group test group was significantly lower,the difference was statistically significant(P<0.01).7.After treatment,the prostate palpation tenderness of the two groups of patients was less than before treatment,the difference was statistically significant(P<0.01),and the test group was significantly less than the control group,the difference was statistically significant(P<0.05).8.After treatment,the EPS-SPL counts of the two groups of patients increased compared with before treatment,the difference was statistically significant(P<0.01);there was no statistically significant difference between the two groups(P>0.05).conclusion:1.Chinese herbal immunomodulators combined with heat-clearing,dampness and blood-activating therapy are more effective in treating type IIIB CP than the single-use heat-clearing,dampness,and blood circulation therapy.2.The Chinese medicine immunomodulator Baishao total glycosides capsule improves the clinical efficacy of type IIIB CP,which is related to the regulation of the body’s immune status and the improvement of pain symptoms.
Keywords/Search Tags:ⅢB prostatitis, damp-heat stasis, clinical research, traditional Chinese medicine immunomodulator, heat-clearing,dampness and blood-activating therapy, immune regulation
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