| Tonifying kidney, clearing damp-heat and activating blood is an effective method to treatchronic glomerulonephritis, which has been summarized by professor Sun Wei from hislong clinical practice. According to the clinical observation and study, the clinical effect hasbeen more verified by this method.Objective:Explore the clinical significance of the differentiation of TCM based on the pathologicalclassification in the combination of TCM with western medicine. Observing the clinicaleffect oftonifying kidney, eliminate damp-heat and promoting blood flow.Method:Theory study and clinical investigation were involved in this study. Selecting andanalyzing classic and morden articles were the main methods of theory study. In clinicalinvestigation, professor Sun's experience on the treatment of CGN was summarized first.Then 100 patients with chronic glomerulonephritis underwent renal biopsy and the resultswere compared with syndromes differentiated referring to the standard of differentiationestablished in 2006, were mainly treated by the method of tonifying kidney, clearingdamp-heat and activating blood. The symptomatic scores and main laboratory indexes wererecorded and analyzed before and after the treatment.Results:Kidney insufficiency, damp (heat) and blood stasis were the main mechanisms of CGN.Kidney insufficiency was the base of occurrence. Damp (heat) and blood stasis was the keymechanisms of progression. So tonifying kidney, cleariny damp-heat and activating bloodwere the main methods of treatment on CGN. After the treatment, the results show that therecovery rate was 18％, the marked rate was 44％, the effective rate was 26％, theimprovement rate was 88％.Compared with before treatment, the total score of symptomwas obviously decreased(P＜0.01), so did urine protein and urianary sediment RBC(P＜0.05), but there was no significant change in hematuria.Conclusion:Tonifying kidney, clearing damp-heat and activating blood is an effective method to treatchronic glomerulonephritis, which can obviously improve symptom, tone up physical force,enhance immunity, and decrease urine protein and urinary sediment RBC. The relevancebetween the syndrome differentiation of TCM and pathological type is of great help toobjectification, standardization and quantification of the patterns, it thus may enhance theefficacy of TCM and promote the communication between TCM and Western medicine. |
