Clinical Observation On The Treatment Of CHF With Gastrointestinal Dysfunction(Qi-Yin Deficiency And Blood Stasis) In The Elderly With The Formula Of Benefitting Qi,Nourishing Yin And Activating Blood

Objective: To observe the clinical efficacy of the formula of benefitting Qi,nourishing Yin and activating Blood in the treatment of chronic heart failure with gastrointestinal dysfunction in the elderly(Qi-Yin deficiency and Blood stasis evidence).Methods:Seventy-two patients diagnosed with CHF with gastrointestinal dysfunction were randomly divided into 36 patients in the treatment group and 36 patients in the control group.Both groups were given conventional Western medical treatment for CHF in the elderly,and the treatment group was given the formula of Beneficial Qi,Nourishing Yin and Invigorating Blood for 14 days.The clinical efficacy of the treatment was evaluated by comparing the TCM syndrome score,Gastrointestinal Symptom Rating Scale(GSRS),Minnesota Heart Failure Quality of Life Scale(MLHFQ),N-terminal B-type natriuretic peptide(NT-pro BNP)level,6-minute walking distance,left ventricular ejection fraction(LVEF)and cardiac function rating of the two groups before and after treatment.Result:After treatment,the TCM symptom score,GSRS score and MLHFQ score decreased significantly(P < 0.05),and NT-pro BNP level,6-minute walking distance,left ventricular ejection fraction and cardiac function classification improved significantly(P < 0.05)in both groups compared with the pre-treatment period,and the total TCM symptom score,GSRS score,MLHFQ score,NT-pro BNP level,6-minute walking distance and cardiac function classification improved significantly(P < 0.05)in the treatment group compared with the control group.The total TCM symptoms,GSRS score,MLHFQ score,NT-pro BNP level,6-minute walking distance and cardiac function classification improved significantly in the treatment group compared with the control group(P < 0.05),and the efficacy of TCM symptoms,GSRS reduction rate and cardiac function efficiency were significantly better in the treatment group than in the control group(P < 0.05),while there was no significant difference in the efficacy of left ventricular ejection fraction between the two groups(P > 0.05).Conclusion: The formula of benefitting Qi,nourishing Yin and activating Blood can improve clinical symptoms,GSRS score,serum NT-pro BNP,6-minute walking distance,cardiac function classification and improve patients’ quality of life in elderly patients with chronic heart failure with gastrointestinal dysfunction(Qi-Yin deficiency and Blood stasis evidence).