Analysis Of Axial Length,Choroidal Thickness And Dominant Eye In Central Serous Chorioretinopathy

PURPOSEThe aim of this study is to analyze the axial length(AL),refractive status,choroidal thickness,and dominant eye of patients with central serous chorioretinopathy(CSC),and to find the possible pathophysiological mechanisms.To provide a new direction for the treatment of CSC and improve the prognosis.METHODS27 eyes of 26 patients with CSC and 27 age-matched healthy control eyes were included in the study.The AL was measured by IOL Master.The refractive status was measured by automatic refractometer,and was converted into analysable data,spherical equivalent(SE).The subfoveal choroidal thickness(SFCT)was measured by optical coherence tomography-enhanced depth imaging(OCT-EDI).The dominant eye was examined by the pinhole method.CSC patients were divided into hyperopia CSC group and myopia CSC group according to the refractive status.And according to the course of disease,CSC patients were divided into acute CSC group and chronic CSC group.After the statistical data was analyzed by SPSS software,all the data of CSC patients was compared with the data of normal control group,to observe whether there is a statistical difference between the CSC group and the normal control group.RESULTSAmong these 26 CSC patients,20 were male and 6 were female.The ratio of male to female is 3:1.There were 25 patients with unilateral CSC and 1 patient with bilateral CSC.Among the 27 eyes of CSC,21(77.78%)eyes were acute CSC and 6(22.22%)eyes were chronic CSC.18(66.67%)eyes were myopia,and 9(33.33%)eyes were hyperopia.The proportion of CSC occurred in the dominant eye was about 68.00%.The AL of the acute CSC group(median 23.23 mm,interquartile range 1.32 mm)was significantly shorter than the control group(median 23.685 mm,interquartile range1.74 mm;P <0.01),and the AL of the hyperopia CSC group(medium median22.94 mm,interquartile range 1.22mm)was significantly shorter than the control group(median 23.685 mm,interquartile range 1.74mm;P <0.01).SFCT was significantly thicker in all CSC groups compared with control group(P <0.01).There was no significant difference in SE among these CSC groups except CSC group with hyperopia compared with control group.CONCLUSIONSThe unilateral CSC usually occurred in the dominant eye.In clinical practice,CSC mostly occurred in patients with mild hyperopia,short AL,and thick SFCT.Compared with control group,acute CSC patients and hyperopia patients had shorter AL,while acute CSC,chronic CSC,hyperopic CSC,and myopic CSC patients had thicker SFCT.There was no significant difference in SE among these CSC groups except CSC group with hyperopia compared with control group.