Effects Of Inspiratory Muscle Training On Lung Function,diaphragm Function And Exercise Capacity In Lung Transplant Recipients

Objective: To investigate the effects of inspiratory muscle training on pulmonary function,diaphragm function and exercise capacity in lung transplant patients.Methods: A total of 44 patients after lung transplantation were assigned to the standard pulmonary rehabilitation(PR)+ inspiratory muscle training(IMT)group(PR + IMT group,n = 22)or the standard pulmonary rehabilitation group(PR group,n = 22).All patients received supervised standard pulmonary rehabilitation twice a day,5 days a week,for 4 weeks.the PR + IMT group received inspiratory muscle training in addition to the standard pulmonary rehabilitation program.MIP,MEP,lung function,diaphragm thickness and mobility were measured in each patient preoperatively,postoperatively after decannulation,four weeks of postoperative training and three months postoperatively,and 6WMD preoperatively,four weeks of postoperative training and three months postoperatively.Results: MIP,MEP,FVC,FVC(%),FEV1,FEV1(%),diaphragm thickness and mobility of patients in the PR + IMT group first showed a decrease postoperatively and gradually increased at four weeks of postoperative training and three months postoperatively,which was statistically significant(P<0.05).MIP,MEP,FVC,FVC(%)diaphragm thickness and mobility of patients in the PR group first showed a decrease postoperatively and gradually increased at four weeks of postoperative training and three months postoperatively.There was a statistically significant decrease in MIP,MEP,FVC,FVC(%)diaphragm thickness and mobility in the PR group,which first decreased after surgery and gradually increased at four weeks and three months after training(P<0.05).The improvement in MIP,MEP,FVC,FVC(%),FEV1,FEV1(%),diaphragm thickness and mobility and 6WMD were better in the PR + IMT group than in the PR group at four weeks and three months postoperatively,with statistically significant differences(P<0.05).The improvement in MIP,MEP,FVC(%),FEV1,FEV1(%)was statistically better than the PR group.Conclusions: Lung transplantation decreases diaphragm function,and four weeks of postoperative pulmonary rehabilitation can improve exercise capacity,lung function and diaphragm function in lung transplant patients,and inspiratory muscle training can further improve lung function,diaphragm function and exercise capacity and increase the benefits of pulmonary rehabilitation in postoperative lung transplant patients.