Correlation Analysis Between Ba-PWV And Fasting Blood Glucose In Patients With Angina Pectoris After PCI And The Distribution Of TCM Constitution

Purpose: This study analyzed the changes of brachial-ankle pulse wave velocity(ba-PWV),fasting blood glucose and other risk factors of angina pectoris in patients with coronary heart disease after percutaneous coronary intervention(PCI),and explored the distribution of TCM constitution in patients with angina pectoris after PCI.It provides the basis for early prediction of the trend of fasting blood glucose in patients with angina pectoris after PCI and early protection.To provide ideas for TCM treatment and nursing of coronary heart disease after PCI.Material and method: 149 patients with angina pectoris after PCI taken to the outpatient department and wards in the first Department of Cardiology in the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from December 2019 to December 2020 were selected.The general data of these patients was collected,with the results of blood glucose and fat recorded and classification and decision table of TCM constitutions filled in.The ba-PWV of the patients was tested.And then the patients were divided into two groups,which were mild lesion group(ba-PWV < 1600cm/s)and severe lesion group(ba-PWV?1600cm/s)based on the evaluation of the degree of atherosclerosis according to the ba-PWV index.The difference of the risk factors of angina pectoris after PCI and the distribution of TCM constitutions were compared between the two groups.Excel was used for data processing,and SPSS Statistics 22 was used for data analysis.Mean ± standard deviation was used for the description of measurement data,and independent sample t test was used for statistical inference.For the description of enumeration data,the frequency and constituent ratio were used,with the chi-square test used statistical inference.If the theoretical frequency N<40,then Fisher exact probability test will be used.Logistic regression was used to analyze the influencing factors of ba-PWV in recurrent angina pectoris after PCI.Spearman rank correlation was used to analyze the correlation between biochemical indexes and ba-PWV.Inspection level ?=0.05,P<0.05 represented that the difference was statistically significant.P<0.01 represented that the difference was conspicuous.This study has been reviewed by the IRB of The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine.Results:1.In the univariate analysis of general data,compared with patients with ba-PWV<1600cm/s,there were significant differences in the proportion of elderly people and the proportion of manual workers in patients with ba-PWV?1600 cm/s(P < 0.05),but there were no significant differences in gender,marital status,smoking and BMI index(P > 0.05).Spearman correlation analysis showed that age was significantly positively correlated with ba-PWV among the risk factors of angina after PCI.There was no correlation between ba-PWV and gender,marital status,occupation,smoking,BMI index.2.In the single factor analysis of blood glucose and blood lipids,compared with the ba-PWV<1600cm/s group,the difference of FPG and LDL-C levels in the ba-PWV?1600cm/s group was statistically significant(P<0.05).There was no significant difference in HDL-C,CHOL,TG and OGTT between the two groups(P>0.05).Binary logistic regression analysis showed that FPG,PPG and LDL-C were the influencing factors of ba-PWV(P<0.05).Spearman correlation analysis showed that FPG,PPG,glucose tolerance and LDL-C were positively correlated with ba-PWV.3.The phlegm-dampness constitution(30.20 %),yang deficiency constitution(18.79 %)and qi stagnation constitution(17.45 %)were the most in patients with angina pectoris after PCI.Among the other biased constitutions,yin deficiency constitution(12.08 %),blood stasis constitution(6.7 %),qi deficiency constitution(4.02 %),damp-heat constitution(2.01 %)and special intrinsic constitution(0.67 %).Among them,the mild sclerosis group was mostly phlegm-dampness(27.27 %),yang deficiency(18.18 %),qi stagnation(14.55 %)and blood stasis(14.55 %).The severe sclerosis group was mostly phlegm-dampness(31.39 %),yang deficiency(19.19 %)and qi stagnation(19.19 %).Conclusion:1.In patients with angina pectoris after PCI,ba-PWV was significantly positively correlated with FPG,and was also correlated with age,FPG,PPG,OGTT abnormalities and LDL-C.Age,FPG,PPG and LDL-C were the influencing factors of atherosclerosis.2.In patients with angina pectoris after PCI,the higher the level of ba-PWV,the higher the fasting blood glucose.ba-PWV has the trend of predicting the changes of fasting blood glucose in patients with angina pectoris after PCI.3.Patients with angina pectoris after PCI mainly have phlegm-dampness constitution,yang deficiency constitution and qi stagnation constitution;Patients with ba-PWV<1600cm/s after PCI angina pectoris in addition to the above three types of constitution as the main body type,still common blood stasis;Phlegm-dampness constitution was the main constitution type in patients with angina pectoris after PCI with ba-PWV?1600 cm/s.