Clinical Observation Of Kuanxiongchangfeiyin In The Treatment Of Chronic Pulmonary Heart Disease With Deficiency Of Both Qi And Yin And Phlegm-heat Obstructing The Lung

Objective:Based on the theory of"Chest binding syndrome",the clinical efficacy of western medicine combined with Kuanxiong Changfei decotion in patients with chronic pulmonary heart disease(cor pulmonale)with the syndrome of phlegm-heat obstructing lung and qi-yin deficiency were observed,thus providing the basis for the clinical application,in order to provide reference in the treatment of cor pulmonale.Methods:after assessment,64 cases were randomly divided into two groups.The control group was treated with oxygen therapy,respiratory support,anti-infection,phlegm dispelling,spasmolysis,anticoagulant,anti-heart failure and other routine western medicine.The treatment group was treated with extra Kuanxiong Changfei decotion for 10 days.By systematically comparing the changes of clinical comprehensive curative effect,TCM symptom score,physical sign score,self-living ability score and CRP?Pa O₂?NT-pro BNP?HCT before and after treatment,the difference of curative effect between the two groups was evaluated.SPSS26.0 software is used to analyze the data.Result:1.Clinical efficacy evaluation:the treatment group's total effective rate of is 93.75,while the control group is 71.87,After statistical analysis,there exist significant difference in total effective rate between two groups(P=0.004<0.05),the treatment group has better clinical efficacy than control group.2.Syndrome score evaluation:comparing with the two groups in syndrome score before and after treatment,it is discovered that both groups can improve symptoms score(P<0.01),and the treatment group is better than the control group(P<0.01).The treatment group improved cough expectoration,sputum,wheezing,chest tightness,palpitation,thirsty,bitter taste,constipation,abdominal distension,fatigue and anorexia better than the control group(P<0.05),but two groups have same efficacy in improving short red urine.3.Physical sign score evaluation:through the comparison of the two groups before and after treatment,it is considered that the two groups can improve the physical sign score(P<0.01),the improvement of edema(P=0.698)and heart rate(P=0.799)is same in two groups,but the effect of treatment group in improving dry and wet rale,cyanosis,respiration and posture was better than control group(P<0.05).4.Blood test evaluation:two groups can significantly improve CRP?HCT?Pa O₂?NT-pro BNP(P<0.01),after treatment,treatment group has better improvement than control group in CRP(P<0.01),as so as in the comparison of Pa O₂,NT-pro BNP and HCT(P<0.05).5.The self-living ability score of the two groups was lower than that before treatment(P<0.05),indicating that the self-living ability of the two groups was improved,and the treatment group has better self-living ability score than that of the control group after intervention(P=0.008<0.01).Conclusion:Kuanxiong Changfei decotion combined with western medicine routine treatment can effectively improve the symptoms,physical signs,blood microcirculation and anoxic state of patients with pulmonary heart disease,improve cardiac function and improve self-living ability.The curative effect is better than that of simple western medicine group.It can provide a reference for the treatment of chronic pulmonary heart disease(cor pulmonale)with the syndrome of phlegm-heat obstructing lung and qi-yin deficiency,which is worthy of clinical application.