| Objective Using data mining technology to summarize the rules of Professor Wang Bangcai’s medications for constipation and learn his thoughts on the diagnosis and treatment of constipation,then to explore the methods of inheriting and promoting the excellent clinical experience of veteran TCM physicians under the background of the information age.Methods This study was based on the TCMISS(v2.5).By collecting 400 first cases of constipation patients diagnosed and treated by Professor Wang Bangcai from November 2019 to December 2021 into the software database.Then use the software to perform frequency statistics,association analysis and hierarchical clustering analysis on the data.Results 1.In 400 cases,there were more women than men.And their age was mainly middle-aged and elderly.Syndromes of them were mainly Yin deficiency and intestinal dryness,Intestinal qi stagnation and Intestinal excess heat.2.Among the 400 prescriptions,involving 133 kinds of traditional Chinese medicine and 3620 times frequency of herbs.Their four characters are mainly concentrated in the three flavors of warm,gentle and cold.Their five tastes are concentrated on the bitter,sweet and spicy.The main meridians are the spleen and stomach,and the large intestine,liver,lung meridians are second.3.Through frequency statistics,there were 10 kinds of herbs with frequency more than 100 times are obtained.40 groups of medication patterns and 34 groups of associated herb groups are obtained based on association rules.8500 groups of herb associations are obtained through hierarchical clustering analysis,of which 80 groups of herb combinations have correlation coefficients greater than 0.01.Based on this,complex system entropy cluster analysis was performed to obtain 14 groups of potential core herbs association.And 7 new prescriptions were obtained after unsupervised entropy hierarchical cluster analysis.Conclusions This study preliminarily excavated and summarized that Professor Wang Bangcai’s prescriptions for treating constipation are mostly based on Zengye Decoction and Xiaochengqi decoction,and then cut the ancient and modern famous prescriptions according to the characteristics of patients’ diseases and syndromes,pay attention to the rise and fall of Qi mechanism,make good use of gentle tonifying,Xinrun curing dryness and other treatment methods,and send prescriptions to cooperate with each other with the methods of Invigorating Qi,nourishing Yin blood and regulating qi mechanism.The medicine is simple and effective. |