The Effect Of Peripheral Blood Eosinophil Count On The Benefit Of Pulmonary Rehabilitation In COPD Patients

Objective : To evaluate the effect of different peripheral blood eosinophil counts on the benefit of comprehensive pulmonary rehabilitation in COPD patients.Methods:COPD patients in the First Affiliated Hospital of Chongqing Medical University were randomly divided into rehabilitation group and control group.The two groups were divided into two subgroups according to the percentage of blood eosinophil counts(EOS≥2% group and EOS<2% group).At the end of lung rehabilitation and the 6th month after lung rehabilitation treatment,the patients were followed up for 6MWD,CAT score,and Borg score.Results : A total of 37 patients obtained complete data,19 in the rehabilitation group and 18 in the control group.Pulmonary rehabilitation and blood eosinophil count level had an interactive effect on 6MWD and CAT scores at the end of rehabilitation treatment(P<0.05),and,under different intervention measures,the COPD patients with different blood eosinophil count levels had interactive effects on 6MWD and CAT scores.Patients with blood EOS≥2% improved more in 6MWD and CAT scores after pulmonary rehabilitation(P<0.05).On the 6th month after rehabilitation treatment,there was an interactive effect between lung rehabilitation and blood eosinophil count level on 6MWD、CAT scores and Borg scores(P<0.05).and,under different intervention measures,the COPD patients with different blood eosinophil count levels had interactive effects on 6MWD 、 CAT scores and Borg scores.Patients with blood EOS≥2% improved more in 6MWD 、 CAT scores and Borg score after pulmonary rehabilitation(P<0.05).Conclusion:For COPD patients,rehabilitation training can improve exercise ability,reduce symptoms and fatigue.COPD Patients with EOS≥2% benefit more from rehabilitation training than those who EOS<2%.