Meta-analysis Of The Effectiveness Of Pulmonary Rehabilitation Training On Patients With Acute Exacerbation Of Chronic Obstructive Pulmonary Disease

Objective:The high fatality rate and high disability rate of patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)have attracted more and more attention in the world.In this study,meta-analysis was used to analyze the effects of pulmonary rehabilitation training on activity,pulmonary function,dyspnea and quality of life in patients with AECOPD.Methods:PubMed,Cochrane Library,Web of Science,Embase,(CNKI),Wanfang database,VIP database and Chinese biomedical literature database were searched by computer for the period from January 2000 to January 2020.Randomized controlled trials(RCT)about the efficacy of pulmonary rehabilitation training on AECOPD patients were collected.According to the inclusion and exclusion criteria,literature screening and data extraction were carried out independently,and meta-analysis was carried out with RevMan 5.3 software.Results:Finally,11 articles were included,and Meta-analysis results showed that pulmonary rehabilitation training is significantly better than conventional treatment in improving the6-min walking distance(6MWD)MD=41.60(95% CI 27.78to55.43,P <0.05),the first second of effort Forced expiratory volume in the first second/Forced vital capacity(FEV1/FVC)MD=3.24(95% CI 2.27to4.22,P <0.05),percentage of FEV1(FEV1%)MD=2.05(95% CI-0.01to4.11,P = 0.05),Modified British Medical Research Council(mMRC)MD=-0.34(95% CI-0.43to-0.26,P <0.05),Borg score MD=-0.41(95% CI-0.58to-0.24,P <0.05),Chronic obstructive pulmonary disease assessment test(CAT)MD=-4.77(95 % CI-6.19to-3.36,P <0.05),and the difference is statistically significant.However,there was no statistically significant difference in pulmonary rehabilitation training in improving the FEV1 MD=0.06(95% CI-0.02to0.15,P=0.14),FVC MD=0.11(95% CI-0.05to0.28,P=0.16),St George's respiratory questionnaire score(SGRQ)MD=-11.26(95% CI-23.19to0.68,P=0.06).Conclusion:Pulmonary rehabilitation training can improve the dyspnea,activity ability,pulmonary function and quality of life of patients with AECOPD.It can be actively promoted under the guidance of multi-disciplinary medical staff.