Huoxue Quban Decoction Combined With Traditional Chinese Medicine Mold In The Treatment Of Chloasma Of Liver Stagnation And Blood Stasis Type

Objective: The clinical efficacy and safety of Huoxue Quban Decoction combined with traditional Chinese medicine mold were evaluated by comparing Huoxue Quban Decoction combined with traditional Chinese medicine mold and simple oral administration of Huoxue Quban Decoction and simple traditional Chinese medicine mold in the treatment of liver-stagnation and blood stasis type chloasma.In order to provide effective clinical treatment ideas and methods for the treatment of chloasma in the future.Method: According to the relevant diagnosis and treatment standards,66 cases of liver stasis and blood stasis type chloasma patients were selected,and then they were numbered according to the order of treatment time,and randomly divided into inverted membrane group,traditional Chinese medicine group and combined group.The Chinese medicine mask was applied to the inverted membrane group for2 times a week,and the Chinese medicine group was given the Huoxue freckle decoction,2 times a day,150 ml each time,the combined group was treated with Huoxue Qu ban decoction and Chinese medicine mask.The total treatment course of the three groups is 12 weeks;observe and record the changes of the patient’s skin lesion area,color,total area score,DLQI score,and adverse reactions after 4 weeks,8weeks,and 12 weeks of treatment.At the end of the course of treatment,the cured and markedly effective patients were followed up for three months to observe the recurrence.All cases met the inclusion criteria.There was no significant difference in age and course of disease among the combined group,the inverted group and the traditional Chinese medicine group.Result: During the experiment,63 cases were selected for statistical analysis,including 20 cases in the combination group,21 cases in the inverted membrane group and 22 cases in the traditional Chinese medicine group.The total area of skin lesions was calculated according to the total area and color of skin lesions,and the decrease index of total area of skin lesions was calculated to evaluate the efficacy of three months before and after treatment.(1)The three groups of patients were not statistically significant in age,disease course,skin lesion area before treatment,color,total area score,and DLQI score(P>0.05),and they were comparable.(2)There were significant differences in the total efficacy of the three groups after 12 weeks of treatment(P < 0.05),and in the pairwise comparison,there were significant differences between the combined group,the inverted membrane group and the traditional Chinese medicine group.The cure rate of the combined group was 20%,the effective rate was 55%,and the effective rate was 5%;the cure rate of the inverted membrane group was 4.8%,the effective rate was9.5%,and the effective rate was 6%;the cure rate of the traditional Chinese medicine group was 4.5%,the effective rate was 36.4%,and the effective rate was 27.3%.(3)Recurrence rate: in the combination group,15 cases were cured and markedly effective,2 cases recurred;in the inverted membrane group,6 cases were cured and markedly effective,1 case recurred;in the traditional Chinese medicine group,7 cases were cured and markedly effective,1 case recurred.There was no significant difference among the three groups(P > 0.05).(4)In terms of adverse reactions: no adverse reactions were found in the combined inverted model group(combined group),and 1 case occurred in the simple inverted model group and the oral Chinese medicine group respectively.Conclusion:1.Huoxue Quban decoction combined with traditional Chinese medicine mold in the treatment of liver stagnation and blood stasis type chloasma is better than simple traditional Chinese medicine oral and traditional Chinese medicine mold external application in improving skin lesions and DLQI of chloasma.2.Huoxue Quban decoction combined with traditional Chinese medicine mold is an effective method in the treatment of chloasma of liver stagnation and blood stasis type,which is safe and reliable and worthy of promotion.