Risk Factors Of Atherosclerosis In Outpatients With Periodontal Specialty

Objective:Atherosclerosis(AS)is an inflammatory disease in the blood vessels and chronic periodontitis(CP)is a common inflammatory disease in the oral cavity.Does the periodontal inflammatory process intersect with the AS process and is the degree of CP inflammation a risk factor for AS? Therefore,this research by collecting oral periodontal of hospital patients with chronic periodontitis,but not with other systemic diseases of the periodontal clinical indexes,blood lipids and c-reactive protein(CRP)and carotid artery plaque index,make a clear definition of the severity of CP and AS the relationship between the related risk factors,to clarify AS soon AS possible on periodontal status has positive effect to AS risk factors for prevention.Methods:1.A total of 86 patients,including 37 females and 49 males,aged 27-78 years,who were clinically diagnosed as CP without other systemic diseases in the Department of Periodontics,Stomatological Hospital of Shanxi Medical University from May,2019 to December,2019,were selected.2.The general data collected included age,sex,height,weight,smoking habits,oral hygiene behavior,and education level.All teeth(except the third molar)were examined with a periodontal probe by the same professionally trained periodontist at 6 sites per tooth,and the following clinical indicators were assessed: probing depth(PD),bleeding on probing(BOP),and clinical attachment loss(CAL).According to the classification criteria of periodontitis published by the American Academy of Periodontology(AAP)in 2018,all patients were classified for the degree of periodontitis.3.According to the patients’ physical examination report,the four lipids of the patients were recorded,including serum triglyceride(TG),total cholesterol(TC),high-density lipoprotein(HDL),low-density lipoprotein(LDL),fasting blood glucose(FPG),CRP,and whether there was plaque formation in the carotid artery.Results:1.One-way ANOVA showed that age,brushing times in a day,CRP and carotid plaque formation among the three groups showed an increasing trend with the increase of the degree of periodontal inflammation,with statistically significant differences(P<0.05),while there were no statistically significant differences in gender,smoking and fasting blood glucose(P>0.05).2.Comparison of blood lipid levels: the levels of TC and LDL among the three groups showed an increasing trend with the increase of the degree of periodontitis,with statistically significant differences(P<0.05),while the differences in TG and HDL showed no statistically significant differences(P>0.05).3.Comparison of periodontal indexes: The levels of PD,BOP and CAL among the three groups showed an increasing trend with the increase of the degree of periodontal inflammation,with statistical significance(P<0.05).Conclusions:1.With the aggravation of inflammation,the serum CRP level in patients with periodontitis increases,and the risk of AS plaque formation also increases.2.The degree of inflammation in periodontitis is positively correlated with the levels of TC and LDL.3.CP is a risk factor for AS.