| Objective:To observe the clinical effect of silver needle heat conduction combined with external application of Shenjin liquid on knee osteoarthritis caused by blood stasis.Methods:Ninety patients with knee osteoarthritis of blood stasis obstruction type were selected from the Department of Orthopedics and Traumatology,Fuzhou Hospital of Traditional Chinese Medicine Affiliated to Fujian University of Traditional Chinese Medicine.They were randomly divided into silver needle group(silver needle heat conduction therapy),stretching muscle liquid group(simple stretching muscle liquid for external use)and silver needle +stretching muscle liquid group(silver needle heat conduction combined with stretching muscle liquid for external use),with 30 cases in each group.Through statistics and analysis of the scores of knee osteoarthritis clinical symptoms grading quantitative table,TCM syndrome grading quantitative table,knee WOMAC score(including pain,stiffness,joint function and total score)and safety observation before treatment,after the first course of treatment,after the second course of treatment and after the fourth course of treatment in the three groups,Scientifically evaluate the feasibility,effectiveness and safety of silver needle heat conduction combined with external application of Shenjin liquid in the treatment of knee osteoarthritis caused by blood stasis,and judge and compare the curative effects of TCM syndromes and clinical comprehensive curative effects of the three groups.Results:1.There were no shedding cases in the three groups during the test.Before treatment,the three groups had no significant difference in general clinical data,scores of knee osteoarthritis clinical symptoms grading quantitative table,scores of TCM syndrome grading quantitative table,and knee WOMAC scores(including pain,stiffness,joint function and total score)(P >0.05),and the three groups were comparable.2.The research results show that the evaluation and analysis of the three groups on the scores of the clinical symptom grading quantitative table of knee osteoarthritis,the scores of the TCM syndrome grading quantitative table,and the WOMAC score of the knee joint(joint function,total score)are consistent.Intra-group comparison: There were significant differences between the silver needle group and the silver needle + Shenjin liquid group before and after treatment and in each course of treatment within the group(P < 0.05).Before and after treatment,there was no significant difference in the intra-group comparison after the second and fourth courses of treatment in the Shenjin liquid group(P > 0.05),but there were significant differences in each course of treatment in the other groups(P < 0.05).Inter-group comparison: There were significant differences among the three groups after the first,second and fourth courses of treatment(P < 0.05).It shows that in the improvement of clinical comprehensive symptoms,TCM syndromes and joint function of knee osteoarthritis,the early curative effects of silver needle group and silver needle + Shenjin liquid group are significant,and their curative effects tend to continue to improve with the progress of treatment course.The early curative effect of Shenjin liquid group was obvious,but with the progress of treatment course,its curative effect did not show a trend of continuous improvement.In the comparison of the overall curative effect of the three groups after treatment,the silver needle+ Shenjin liquid group is better than the silver needle group and the Shenjin liquid group(P <0.05),and the silver needle group is better than the Shenjin liquid group(P < 0.05).3.In the comparison of WOMAC score(pain)of knee joint among the three groups,the comparison within the group: the silver needle group and the silver needle + Shenjin liquid group,before and after treatment,and the comparison of each course of treatment within the group,the difference is significant(P < 0.05).Before and after treatment,there was no significant difference in the intra-group comparison after the second and fourth courses of treatment in the Shenjin liquid group(P > 0.05),but there were significant differences in each course of treatment in the other groups(P < 0.05).Comparison between groups: In the comparison between the three groups after the first and second courses of treatment,there was no significant difference between the silver needle group and the Shenjin liquid group(P >0.05),and the silver needle + Shenjin liquid group was compared with the silver needle group and the Shenjin liquid group.The difference is significant(P < 0.05);There were significant differences among the three groups after the fourth course of treatment(P < 0.05).It shows that in terms of pain relief of knee osteoarthritis,the early curative effects of silver needle group and silver needle + Shenjin liquid group are significant,and their curative effects have a tendency to continue to improve with the progress of treatment course.The early curative effect of Shenjin liquid group was significant,but with the progress of treatment course,its curative effect did not show a trend of continuous improvement.In the comparison of the overall curative effect of the three groups after treatment,after the first and second courses of treatment,the silver needle + Shenjin liquid group was better than the silver needle group and the Shenjin liquid group(P < 0.05),and the silver needle group and the Shenjin liquid group had no difference in curative effect(P > 0.05);After the fourth course of treatment,the silver needle + Shenjin liquid group was superior to the silver needle group and the Shenjin liquid group(P < 0.05),and the silver needle group was superior to the Shenjin liquid group(P <0.05).4.In the comparison of WOMAC score(stiffness)of knee joint among the three groups,the comparison within the group: silver needle group and silver needle + Shenjin liquid group,before and after treatment,after the first,second and fourth courses of treatment in the two groups were compared with before treatment,the difference was significant(P < 0.05);After the first and second courses of treatment,there was no significant difference after the second and fourth courses of treatment(P > 0.05).After the first and fourth courses of treatment,the difference was significant(P < 0.05).Before and after treatment,after the first and second courses of treatment in the group were compared with those before treatment,after the second and fourth courses of treatment were compared with those after the first course of treatment,and after the second and fourth courses of treatment,there was no significant difference(P >0.05);After the fourth course of treatment,the difference was significant compared with that before treatment(P < 0.05).Inter-group comparison: There was no significant difference between silver needle group and silver needle + Shenjin liquid group after the first,second and fourth courses of treatment(P > 0.05).There was a significant difference between the silver needle group and the Shenjin liquid group(P < 0.05);There was a significant difference between the silver needle + Shenjin liquid group and the Shenjin liquid group(P < 0.05).It shows that in the improvement of stiffness of knee osteoarthritis,the early curative effect of silver needle group and silver needle + Shenjin liquid group is obvious,and its curative effect still has a tendency to continue to improve with the progress of treatment course,but the degree of curative effect improvement is not obvious.There is no obvious curative effect in the early stage of Shenjin Liquid group,but with the progress of the course of treatment,it can still improve slightly in the later stage.In the comparison of the overall curative effect of the three groups after treatment,there was no difference between the silver needle group and the silver needle + Shenjin liquid group(P > 0.05),and the silver needle group was superior to the Shenjin liquid group(P < 0.05),and the silver needle + Shenjin liquid group was also superior to the Shenjin liquid group(P < 0.05).5.The curative effects of TCM syndromes in the three groups were silver needle group(90.0%),Shenjin liquid group(76.7%),silver needle + Shenjin liquid group(93.3%).The comprehensive clinical curative effects of the three groups were silver needle group(93.3%),Shenjin liquid group(80.0%)and silver needle + Shenjin liquid group(96.6%).After statistical analysis,the differences are significant(P < 0.05).It is considered that the silver needle + Shenjin liquid group is superior to the silver needle group and the Shenjin liquid group in terms of TCM syndrome curative effect and clinical comprehensive curative effect,and the silver needle group is superior to the Shenjin liquid group.6.There were no adverse events such as needle fainting,needle breakage,needle stagnation,local skin scald or allergy during the test in the three groups.Conclusion:In the treatment of knee osteoarthritis of blood stasis obstruction type,silver needle heat conduction combined with external application of Shenjin liquid has the best clinical comprehensive curative effect compared with simple silver needle heat conduction therapy and simple Shenjin liquid external application treatment,and simple silver needle heat conduction therapy has advantages over simple Shenjin liquid external application treatment. |
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