Clinical Observation Of Buyuan Decoction In Treating Chronic Obstructive Pulmonary Disease With Qi-Yang Deficiency Syndrome In Stable Stage

This research is about to observe the clinical efficacy and safety of Buyuan Decoction in the treatment of chronic obstructive pulmonary disease with Qi-yang deficiency syndrome in stable stage.Specifically,the effectiveness and safety of the patients’ symptoms and signs were compared before and after treatment,and their effectiveness and safety were evaluated to demonstrate the effectiveness and feasibility of applying Buyuan Decoction in the stable stage of chronic obstructive pulmonary disease with Qi-yang weakness syndrome.Methods:A total of 62 patients with chronic obstructive pulmonary disease with Qi-yang deficiency syndrome in stable stage were selected with the diagnostic criteria of Chinese and Western medicine.They were randomly divided into 2 groups according to the random number table method,with 31 cases in the control group and 31 cases in the experimental group.The control group was given conventional Western medicine treatment(salmeterol and ticasone powder inhalation + acetylcysteine effervescent tablets),and the experimental group was treated with Buyuan Decoction on the basis of conventional Western medicine treatment.The course of treatment in both groups was for 2 months.Two months later,the scores of TCM syndromes,6-minute walking distance,lung function,CAT score,m MRC grading and other indicators were collected for the two groups of patients before and after treatment.All data were processed and analyzed using SPSS24.0 statistical software.Results:⑴A total of 62 cases were included in the group.According to the random number table method,they were randomly divided into 2 groups,31 cases in the control group and31 cases in the experimental group.In the course of this study,1 case was eliminated from the experimental group and 1 case was dropped from the control group.The clinical data of 60 patients were finally analyzed.⑵The baseline data comparison of the two groups before treatment(including gender,age,course of disease,lung function,TCM syndrome score)had not significant difference(P>0.05),and it was comparable.⑶After 2 months of drug treatment,there was no significant difference in lung function between the two groups of patients(P>0.05).The CAT scores,m MRC grades,and TCM syndrome scores of the two groups of patients were lower than before,and the 6-minute walking distance of the two groups of patients was increased.The experimental group was better than the control group,and compared with the control group,there were significant differences(P<0.05).After treatment,the total effective rate of the experimental group was 83.3%,and the total effective rate of the control group was 66.7%.The experimental group was better than the control group,and compared with the control group,there was a significant difference(P<0.05).⑷In the course of treatment,there were no obvious abnormalities of the two groups of patients in the vital signs and blood routine,liver function,renal function,etc.The safety evaluation was level 1,and there were no adverse reactions.Conclusion:Western medicine conventional treatment and Buyuan Decoction + Western medicine conventional treatment are both effective in the treatment of chronic obstructive pulmonary disease with Qi-yang deficiency syndrome in stable stage,and it is safe and non-toxic and side-effects,but Buyuan Decoction + conventional western medicine has better curative effect and can be further promoted clinically.