| Objective:Through the project design,verify the famous prescription "Bushen Huoxue decoction" to improve the symptoms of osteoporotic vertebral fracture and regulate the effect of bone formation,bone resorption,pain factors,study the elderly patients with osteoporotic vertebral compression fracture after PKP minimally invasive surgery,determine serum osteocalcin,interleukin 6,tumor necrosis factor α level,record pain score and lumbar dysfunction index score,observe its efficacy and treatment range,and provide theoretical support for clinical fracture patients with Bushen Huoxue decoction to further improve their condition.Methods:From October 2017 to September 2019,a total of 70 patients with osteoporotic vertebral compression fracture and PKP were diagnosed in the second department of bone in Jiangxi Provincial Hospital of Integrated Chinese and Western Medicine,all of them were single vertebral fractures.The 70 patients who met the criteria were divided into two groups according to the order of treatment time: experimental group and control group,35 patients in each group were treated with Bushen Huoxue decoction combined with western medicine(postoperative analgesia for 3 days,anti-osteoporosis,prevention of infection),the control group was treated with western medicine routinely,the experimental group was treated with traditional Chinese medicine for 4 weeks,the observation group was followed up for 3 months,and the two groups were collected before and after treatment general data,visual simulation score(VAS),oswestry dysfunction index score(ODI),BGP,IL-6,TNF-α content(excluding 1 day after operation),and clinical efficacy evaluation of two groups of patients within 3 months after operation.the data of the study were analyzed using sps20.0 statistical software.Results:(1)The two groups general data,such as sex 、 age group、fracture site and compression degree was not statistically significant and could be compared.(2)The comparison of VAS scores between the two groups before treatment showed no significant difference and nostatistical significance(P>0.05).After 2 weeks,1 mouth and 3 mouths of treatment,the VAS scores of the two groups were lower than those before,and the difference was statistically significant(P<0.05),and the VAS scores of the experimental group were lower than those of the control group.In terms of pain improvement,the experimental group was better than the control group.(3)There was no significant difference in ODI scores before treatment between the two groups(P>0.05),the ODI scores were decreased after treatment,and the ODI scores which the two groups after treatment different time nodes were all P<0.05,the difference was statistically significant,and the experimental group recovered better than the control group.(4)The content of BGP,IL-6,TNF-α in the control group and the experimental group decreased after 3 months of treatment,and the content of BGP,IL-6 and TNF-α in the experimental group decreased more quickly than that in the control group after 2 weeks,January and March.The experimental group had more advantages over the control group in improving bone resorption index and bone formation index.(5)In terms of clinical efficacy,the experimental group total effective rate was 94.26%,and the control group was 88.57%,and the experimental group had better clinical effect than the control group.Conclusion: The method of treating osteoporotic vertebral compression fracture with Bushen Huoxue decoction can effectively relieve the symptoms of patients with PKP after operation,and can further improve osteoporosis,low back pain and activity.Bushen Huoxue decoction combined with western medicine routine treatment of senile osteoporotic vertebral compression fracture after surgery is better than western medicine routine treatment.Bushen Huoxue decoction to improve the elderly osteoporosis vertebral compression fracture PKP postoperative symptoms,is safe and effective,can be popularized treatment. |
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