| Objective:Oral lichen planus(OLP)can occur in different oral sites and may have an indirect effect on the initiation of periodontal disease.The presence of periodontal disease may affect the progression or prognosis of OLP.In this study,OLP patients were investigated by questionnaire and oral examination,and oral fluid samples were collected for research and analysis.The aims of this project are:(1)to understand the OLP patients of oral health awareness,knowledge,attitude and behavior;(2)to investigate the relationship between periodontal health and OLP recurrence or aggravation;(3)to preliminarily understand the distribution characteristics of the main suspected periodontal pathogens in the oral cavity of OLP patients.The expected research results will help to understand the relationship between these two common oral diseases and provide necessary scientific basis for their treatment and prevention.Methods:Choosing patients those who visited the department of stomatology of Yan’an Hospital Affiliated to Kunming Medical University,OLP with chronic periodontitis(CP)patients as OLPP group(OLPP group is divided into erosive OLP and non erosive OLP),OLP with chronic gingivitis(CG)were as OLPG group(OLPG group is divided into erosive OLP and non erosive OLP),and accepting periodontitis of oral cavity check as CP group,gingivitis as CG group.Patients with unstable OLP symptoms and obvious pain were assigned as group A,while patients with stable OLP symptoms and no obvious pain were assigned as group B.Through the questionnaire survey to understand the oral health awareness,knowledge,attitude and oral health behavior.Oral examinations including periodontal health were performed.The existence of 6 kinds of suspected periodontal pathogens was detected by Polymerase Chain Reaction(PCR)in the oral specimens of the subjects,and the difference in detection rate was statistically analyzed.Results:The questionnaire survey showed that the correct rates of the frequency,time and method of brushing were 8.45%,11.27%and 14.08%,respectively.The statistical results showed that there was no significant difference between group A and group B in dental caries,wedge-shaped defects,residual roots and crowns,tooth loss and impacted teeth(P>0.05).The difference in CI-S between group A and group B was statistically significant(P<0.05),while the difference between GI and PD was not statistically significant(P>0.05).There was no statistical difference in the incidence of CP and CG between group A and group B(P>0.05).In the detection of 6 suspected periodontal pathogens,the detection rate of Porphyromonas gingivalis(P.g)and Tannerella forsythia(T.f)in OLP with CP group was higher than that in non-OLP group.The detection rate of Treponema denticola(T.d)in non-erosion OLP with CP group was higher than that in non-OLP group,and the detection rate of Fusobacterium nucleatum(F.n)in OLP group was higher than that in non-OLP group.There was no significant difference between the detection rates of 6 bacteria and smoking and drinking(P>0.05).The prevalence of Prevotella nigrescens(P.n)was statistically significant with dietary habits(P<0.05).The detection rates of T.d and T.f in OLP group were statistically significant with the type of periodontal disease(P<0.05).There was no significant difference between the detection rates of 6 bacteria and OLP erosion and non-erosion types(P>0.05).The detection rates of Rg,T.d and T.f were significantly different between the combination types of periodontal disease and OLP(P<0.05),and the combination had the highest detection rate in patients with non-erosive OLP with CP.Conclusion:This study found that most OLP patients had poor oral health awareness,weak knowledge,inactive attitude and poor oral health behavior.Periodontal health was not associated with relapse or exacerbation of OLP.Porphyromonas gingivalis and Tannerella forsythia were easily distributed in OLP patients with CP.Fusobacterium nucleatum is easily distributed in OLP patients.Porphyromonas gingivalis、Treponema denticola and Tannerella forsythia were easily distributed in patients with non-erosive OLP with CP. |
