Clinical Efficacy Of Mild Moxibustion In The Treatment Of Prehypertension (Excessive Accumulation Of Phlegm Dampness Syndrome)

ObjectiveTo evaluate the effect and safety of mild moxibustion in the treatment of prehypertension(excessive accumulation of phlegm dampness syndrome)in order to find a safe and convenient clinical treatment with significant efficacy for prehypertension.MethodA randomized,parallel-controlled research method was adopted in this study.Qualified participants with prehypertension and excessive accumulation of phlegm dampness syndrome were evenly allocated to the treatment group and the control group.The treatment group was treated with mild moxibustion,choose ST3 6,ST40 and KI1,cauterize last for 20 minutes each acupoint.The control group was treated with acupuncture,choose ST36,ST40 and KI1,use twirling draining method every 15 minutes,and the needle was left for 30 minutes.Subjects in both groups were treated once every other day,3 times a week,a course of 12 times in total.Main evaluation measure:blood pressure level.The efficacy was evaluated by the degree of the blood pressure,s decrease.Secondary evaluation indexes:syndrome score of the excessive accumulation of phlegm and dampness in hypertension(TCM syndrome score)and efficacy evaluation was carried out by reduction rate;Duchenne hypertension quality of life scale score.All participants were evaluated before,during and after the treatment by the researchers and adverse reactions were recorded at any time for safety assessment.IBM SPSS Statistics 25 was used for descriptive analysis.Normality tests should be performed prior to the measurement data.T-test was used for the measurement data consistent with the normal distribution while rank sum test was for the measurement data not consistent with the normal distribution.The rank sum test and the chi-square test are applied for the grade data and enumeration data respectively.Repeated measurement analysis of variance was for the total systolic blood pressure,diastolic blood pressure,TCM syndrome score and quality of life score.P<0.05 serves as a standard with a statistical difference.Results66 participants were enrolled from January 2020 to December 2020 in the GuangDong Second Traditional Chinese Medicine Hospital.1 case fell off,and a total of 32 cases were completed in the moxibustion group.1 case fell off and 32 cases were completed in the acupuncture group.A total of 64 cases were finally completed.There were no statistical differences between the two groups at baselines,such as gender,age,systolic blood pressure,diastolic blood pressure,TCM syndrome score and quality of life score(P>0.05)and they were good for comparability.Comparison of the blood pressure:After the treatment,the levels of systolic and diastolic blood pressure in both groups decreased significantly compared with before.The moxibustion group decreased more sharply and faster than the acupuncture group,with a statistical significance(P<0.05).In the moxibustion group,the total effective rate was 96.88%and the marked effective rate was 18.75%.In the acupuncture group,the total effective rate was 65.63%,and the marked effective rate was 18.75%.The clinical efficacy of blood pressure level between the two groups was P<0.05.The difference was statistically significant,indicating that moxibustion had better clinical efficacy in improving the blood pressure level of the PHT patients.Comparison of the TCM syndrome score:After the treatment,the TCM syndrome score of the two groups decreased significantly compared with before.The moxibustion group decreased more sharply and faster than the acupuncture group,with a statistical significance(P<0.05).In the moxibustion group,the total effective rate was 96.88%and the marked effective rate was 43.75%.In the acupuncture group,the total effective rate was 75.00%and the marked effective rate was 9.38%.The clinical efficacy of the TCM syndrome between the two groups was P<0.05.The difference was statistically significant,indicating that moxibustion had better clinical efficacy in improving the TCM syndrome of the PHT patients.Comparison of the quality of life score:After the treatment,the quality of life score of both groups were significantly higher than before.The moxibustion group increase greater and faster than the acupuncture group,with a statistical significance(P<0.05).The researchers observed no serious adverse reactions or adverse events during the whole study,suggesting that the safety of the moxibustion and the acupuncture in the treatment of PHT is worthy of affirming.Conclusions1.Both groups improve the blood pressure,the TCM syndrome and the quality of life effectively and the treatment group works faster and more effectively.2.The mild moxibustion treatment of prehypertension with excessive accumulation of phlegm dampness syndrome has an obvious clinical effect and high safety,which is worthy of promotion.