| Objective:acupuncture plus moxibustion with medicinal cake by Tongxie Yaofang in the treatment of Diarrhoeal irritable bowel syndrome(IBS-D),put forward ideas for TCM mind-regulating acupuncture and moxibustion treatment of IBS-D.Methods: 90 cases meeting the research criteria,according to the random number table they were divided into experimental group and matched group,45 patients in each group.11 cases were lost in the each groups,68 cases were effective,and 34 cases in each group.In the treatment group,acupuncture at points in the mind-regulating group was combined with moxibustion at the umbilical region separated by medicine cakes,while trimebutine maleate tablets were taken orally in the control group.One week was a course of treatment,with a entire of four courses of treatment.The scores of IBS-SSS,fecal time approaching normal for the first time,symptom scores of each course of treatment,Hamilton anxiety,i Hamilton depression and Pittsburgh sleep index scores were statistically analyzed before and after treatment,and the curative effect was evaluated.Results:(1)After 4 courses of treatment,the grade of IBS-SSS in the two sets after therapy were lower than those before,and the grade of the treatment group were lower than those of the control group(P < 0.05).(2)After treatment and intervention,the "time required for the first time to reach normal stool(h)" of patients in the two groups was shorter than that in the control group(P < 0.05),and tended to be about 50 hours.(3)After treatment,the total symptom scores of the two groups were lower than those of the previous course of treatment after 1,2,3 and 4 courses of treatment(P <0.05);There was no significant difference in the total score between the two groups in the first and second courses of treatment(P > 0.05),but the total score of the treatment group in the third and fourth courses of treatment was lower than that of the control group(P < 0.05).(4)After 1 course of treatment,the score of the treatment group was lower than that before(P < 0.05);The grade of celialgia and ventosity in matched group was lower than that before treatment(P < 0.05).The scores of symptoms in the treatment group were lower than those in the matched group(P < 0.05),the score of abdominal pain and distension in matched group was lower than that in treatment group(P <0.05).(5)After 2 courses of treatment,the scores of each symptom in the treatment group were compared with those in the first course of treatment,and the scores of daily defecation and abdominal pain and distension in the treatment group were lower than those in the first course of treatment(P < 0.05).The symptom marks of matched group were compared with that of one course of treatment,celialgia and ventosity was lower than one course of treatment(P < 0.05).The symptom marks of experimental group and matched group were compared,daily cacation score of treatment group was lower than control group(P < 0.05).(6)After 3 courses of treatment,compared with 2 courses of treatment,the scores of fecal shape,abdominal pain and abdominal distension in the treatment group were lower than those in the 2 courses of treatment(P < 0.05).The daily defecation score and secondary symptom score of the control group were lower than those of the2 courses of treatment(P < 0.05).Comparison between treatment group and matched group,Feces shape score in treatment group was lower than matched group(P < 0.05).(7)After 4 courses of treatment,the score of each symptom in the treatment group was compared with that in the 3 courses of treatment,and the score of fecal shape was lower than that in the 3 courses of treatment(P < 0.05).Compared with the three courses of treatment,the scores of fecal shape,abdominal pain and abdominal distension in the control group were lower than those in the three(P < 0.05).Comparing between treatment group and matched group,Feces shape score in treatment group was lower than matched group(P < 0.05).(8)After treatment,compared with before treatment HAMA,HAMD and PSQI in the two groups were lower after treatment than before treatment,and treatment group were lower than matched group(P < 0.05).(9)After 4 courses of treatment,comparison of treatment group and matched group,the effective rate of the treatment group was higher than matched group,and the recent recurrence rate of the treatment group was lower than matched group(P <0.05),and the two groups were safe.Conclusion: Mind-regulating acupuncture,plus moxibustion with medicinal cake separated by Tongxie Yaofang and oral trimebutine maleate tablets have curative effects on improving symptoms of IBS-D patients.Combined acupuncture and moxibustion is superior to oral trimebudine in improving IBS-SSS,fecal shape time of first symptom,total symptom score,HAMA,HAMD and PSQI of IBS-D patients,that is,the overall curative effect of acupuncture and moxibustion is better;There was no significant difference between the two treatments in improving the daily defecation frequency and fecal shape of IBS-D patients at the initial stage of treatment.Oral trimebudine has advantages in improving abdominal pain and distension in IBS-D patients in the early stage of treatment,but there is no significant difference with acupuncture in the later stage of treatment.The effective rate of acupuncture combined with drug separation is higher than that of oral trimebudine,the short-term recurrence rate is lower,and the curative effect is better.Mind-regulating acupuncture combined with medicine-separated moxibustion may play a regulating role through multiple channels and multiple targets. |
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