Clinical Analysis Of Liver Function And Myocardial Zymogram In Children With Recurrent Respiratory Tract Infections

Objectiveto analyze the liver function and myocardial zymogram of children with recurrent respiratory tract infections,and to explore the clinical significance of RRTIs determination of liver function and myocardial zymogram in children.MethodsChildren aged 14 years old in Shenyang Children’s Hospital from August 2018 to August 2020 were selected(n=413),including children with physical examination and children with respiratory tract infection.According to the medical history,physical examination and related auxiliary examination,the children were divided into three groups: recurrent respiratory infections group(n = 150),non-recurrent respiratory infection group(n = 150)and healthy group(n = 113).The liver function and myocardial zymogram of the children were measured by AU680 automatic biochemical analyzer,and the clinical data of the three groups were statistically analyzed by SPSS25.0 software.Results1.There was no significant difference in the average age and sex among the recurrent respiratory tract infections group,the non-recurrent respiratory tract infection group and the healthy group(P > 0.05).2.There were significant differences in serum ALT,AST,CK-MB and LDH among recurrent respiratory tract infection group,non-recurrent respiratory tract infection group and healthy group(P < 0.001),but there was no significant difference in serum CK among the three groups(P > 0.001).3.The levels of serum AST,CK-MB and LDH in recurrent respiratory tract infection group were significantly higher than those in non-recurrent respiratory tract infection group and healthy group(P < 0 05),but there was no significant difference in serum ALT between two groups(P > 0 05).4.The levels of serum AST,CK and LDH in patients with recurrent upper suction tract infection were significantly higher than those in patients with recurrent lower respiratory tract infection(P < 0.001),but there was no significant difference in serum ALT and serum CK-MB between patients with recurrent upper suction tract infection and recurrent lower respiratory tract infection(P > 0.001).Conclusions1.The levels of serum ALT,AST,CK-MB and LDH in children with respiratory tract infection were higher than the normal.2.The levels of serum AST,CK-MB and LDH in children with recurrent respiratory tract infection were higher than those in children non-recurrent respiratory infection.3.Children with recurrent respiratory infections may be more likely to cause abnormal liver function and / or abnormal myocardial zymogram than those without recurrent respiratory infections.