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Clinical Study On The Effectiveness And Safety Of PIB Gutong Ointment In Treating Arthralgia

Posted on:2021-05-24Degree:MasterType:Thesis
Country:ChinaCandidate:X Q ZhaoFull Text:PDF
GTID:2504306272494094Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Joint pain refers to he pain of large and small joints.Nature of pain is various,including resting pain and pain after exercise.Joint pain is a common symptom in the world,and its primary disease involves a wide range,there are many types,and the causes are different.There are many common causes of joint pain,such as ligament damage,cartilage damage,joint synovitis,autoimmune disease,strain and pain caused by tumors,joint dislocations,viral infections,osteoarthritis,traumatic joint pain,and pyogenic Arthritis,osteoarthritis,osteoporosis,hematological diseases,vitamin D deficiency,gouty arthritis,rheumatism and rheumatoid arthritis,all of these diseases will appear joint pain.PIB Gutong plaster can treat joint pain caused by various reasons.It is a modern plaster with the effect of removing wind,activating blood circulation,tonifying the network,reducing swelling and analgesic.including Ding Geng Teng,Ephedra,Angelica,Made from sea breeze,frankincense,dried ginger,white peony,panax notoginseng,turmeric,pepper,camphor,cinnamon oil,golden do not change,menthol,this medicine has the functions of expelling wind,promoting blood circulation,collaterals,swelling,and pain relief.The matrix of PIB Gutong plaster is mainly polyisobutylene.This matrix is developed through new technology of transdermal absorption,which makes the patient more comfortable to use and has a higher drug utilization rate.After PIB Gutong plaster uses polyisobutylene as a matrix,the allergy rate of this medicine has decreased by 82%.When PIB Gutong plaster is torn off,it does not pull out sweat and has a small impact on skin damage.From the perspective of medicinal effects,PIB material Gutong plaster is more conducive to drug release,quick onset,safe and non-toxic,low allergy rate,strong stickiness and easy to tear,and does not pull out hair.The clinical study of PIB Gutong plaster under a certain sample,because the sample size of this test is 2897,the effectiveness of the combined drug group is numerically superior to that of the PIB Gutong plaster group and the non-steroidal anti-inflammatory drug group.The pain scores of the three groups continued to decline during the treatment process,and the overall decline of the PIB Gutong plaster was slightly lower than that of the non-steroidal antiinflammatory drug group and the combined drug group.The comparison between the three groups was statistically significant;The pain relief time,pain disappearance time,joint mobility and other aspects were analyzed for the effectiveness of Gutong plaster in treating joint pain.There was no significant difference in the incidence of contact dermatitis,the severity of contact dermatitis,and the pruritus score in the PIB Gutong plaster plaster group and the combined medication group.Bone disorders in PIB have no effect on the health of the subject.From the data results,it can be seen that PIB Gutong plaster has a good effect on the treatment of various joint pains,and has no toxic and side effects.This study is mainly the result of a clinical trial of the effectiveness and safety of PIB Gutong plaster for joint pain.Based on the absence of abnormal reactions,a prospective,intergroup control,and multi-center clinical trial design method for case registration study was used.A clinical trial was developed to further determine the efficacy of PIB Gutong plaster on joint pain in patients with 2897 subjects.
Keywords/Search Tags:Joint pain, PIB Gutong plaster, Clinical Trials, Effectiveness, Safety
PDF Full Text Request
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