| Objective: The aim of this study was to investigate the effects of 12-week brisk walking on circadian rhythm of blood pressure,ambulatory arterial stiffness index,risk of ischemic cardiovascular disease,blood pressure and heart rate during exercise in non-dipper hypertensive subjects.Methods: Twenty-two hypertensive people aged 40-69 with systolic blood pressure of 130-159 mm Hg at rest and nocturnal blood pressure decrease of less than10% were recruited,both male and female.The experiment was divided into two stages.The first stage was to observe the effect of medication:questionnaire survey was conducted,and basic indexes such as fasting blood lipid,resting state blood pressure were measured for the first time without any intervention.The above indexes were measured for the second time 4 months later.The second stage was the 12-week brisk walking exercise intervention: after re-measuring the above indexes,the 24-hour dynamic blood pressure was measured,and the fitness test and the exercise test of increasing load on the power vehicle were carried out.The subjects who meet the inclusion criteria were randomly divided into 13 people in the exercise group and 9people in the control group.All of these measures were measured again in both groups after 3 months of exercise intervention.SPSS25.0 was used for statistical analysis of the data,paired sample T test was used for intra-group comparison,and independent sample T test was used for inter-group comparison.Results:(1)There was no significant change in blood pressure during the first stage of the test(P>0.05);After the second stage exercise intervention,the systolic blood pressure in the exercise group was significantly decreased(131.23±7.68)mm Hg VS(137.38±8.30)mm Hg,(P<0.01),and the risk of ICVD was also significantly decreased(6.89±6.37)%VS(8.73±8.40)%(P<0.05),while there was no significant change in the control group.(2)The decrease rate of nocturnal systolic blood pressure in the exercise group was significantly decreased(9.09±3.93)% VS(2.04±4.04)%(P<0.01),and the variation coefficient of diastolic blood pressure in the daytime was significantly decreased(P<0.05),while there was no significant change in the control group.There was no significant change in ambulatory arterial stiffness index between the exercise group and the control group before and after intervention(P<0.05).(3)In the increasing load exercise of the power vehicle,the systolic blood pressure level of the exercise group after 12 weeks was significantly decreased compared with that before 12 weeks at the 50 W load and at the 1st,3rd,5th,10 th and 15 min of the recovery period(P<0.05).The diastolic blood pressure decreased significantly at the 10 th and15th min of the convalescence period compared with 12 weeks ago(P<0.05).The heart rate decreased significantly at 1min of recovery period compared with 12 weeks ago(P<0.05).The systolic blood pressure in the control group was significantly higher after12 weeks at the 50 w load than before 12 weeks(P<0.05).There was no significant change in diastolic blood pressure or heart rate after 12 weeks(P>0.05).(4)In the related indexes of physical fitness test,the reaction time of exercise group after 12 weeks exercise intervention was significantly decreased(P<0.05),and lower than that of control group(P<0.05).The grip strength of the control group was significantly reduced(P<0.01)compared with that before 12 weeks,and the arm lift was significantly increased in 30s(P<0.05).Conclusion:(1)12 weeks of brisk walking exercise can increase the decrease of nocturnal blood pressure and significantly improve the circadian rhythm of blood pressure in people with non-dipper hypertension.(2)12 weeks of brisk walking reduced the risk of ischemic cardiovascular disease in people with non-dipper hypertension.(3)12 weeks of brisk walking exercise can reduce the increase of blood pressure during exercise in people with non-dipper hypertension and increase the safety during exercise. |
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