Clinical Study Of Sanxian Anshen Prescription In The Treatment Of Female Menopausal Insomnia

Research objective On the basis of consulting ancient and modern literature and summing up clinical experience,this clinical trial proposes to treat female menopausal insomnia with Sanxian Anshen Prescription in order to find a more valuable treatment for this disease.Research method Sixty female patients with menopausal insomnia of Yin-Yang deficiency type who met the criteria of case selection were divided into experimental group and control group by random number table method from March 2018 to December2018 in the outpatient department of encephalopathy of Tai’an Traditional Chinese Medicine Hospital,with 30 cases in each group.The experimental group was treated with Sanxian Anshen Decoction and the control group was treated with oral alprazolam for 28 days.Statistical analysis was made on sleep quality and improvement of climacteric syndrome symptoms on the 28 th day after treatment and the 0th day before treatment in the experimental group,the control group and the two groups.Research findings Compared with the Pittsburgh Scale(PSQI)score group before and after treatment,the P = 0.00 and P value of the two groups were less than 0.01,which showed that the two groups could effectively improve the sleep quality of patients.Before and after treatment,the difference of scale scores between the two groups was P=0.25,P>0.05.There was no statistical significance,indicating that there was no significant difference in the improvement of curative effect between the two groups.The Kupperman scale scores of the two groups before and after treatment and the difference between the two groups before and after treatment were P=0.00,P<0.01,with significant difference.It can be seen that the treatment group is better than the control group in improving menopausal symptoms after treatment.Ridit analysis showed that the 95% confidence interval of Ridit value in treatment group was(0.37-0.58),including 0.5,P>0.05.There was no significant difference between the two groups in improving sleep quality.Ridit analysis showed that the 95% confidence interval of Ridit value in treatment group was(0.09-0.30),excluding 0.5,P<0.05.The difference was statistically significant,indicating that the effect of treatment group on improving menopausal syndrome was better than that of control group.Research conclusion There was no significant difference between Sanxian Anshen Prescription and oral alprazolam in improving insomnia symptoms.Both of them could effectively improve the sleep quality of patients.The curative effect of Sanxian Anshen Decoction on climacteric syndrome is better than that of oral alprazolam.