Analysis Of Risk Factors Of Delayed Gastric Emptying After Pancreaticoduodenectomy

Objective:This article collects the clinical data of patients undergoing pancreaticoduodenectomy,analyzes the related factors of delayed gastric emptying after pancreaticoduodenectomy,and provides reference for clinical prevention and treatment of delayed gastric emptying.Methods:This study retrospectively analyzed the clinical data of patients who underwent pancreaticoduodenectomy from a single medical team of the Department of Hepatobiliary and Pancreatic Surgery of the First Hospital of Shanxi Medical University from June 2014 to November 2020.A total of 70 cases were screened.According to whether DGE occurred after surgery,70 patients were divided into DGE group(n = 18)and non-DGE group(n = 52).Select preoperative,intraoperative and postoperative risk factors that may affect the incidence of DGE after PD for statistical analysis.Among them,preoperative factors mainly include: gender,age,hypertension,diabetes,smoking history,drinking history,preoperative White blood cell count,hemoglobin,total bilirubin,albumin and alanine aminotransferase levels;intraoperative factors mainly include:operation time and intraoperative blood loss;postoperative main factors include: white blood cell count on the first day after surgery,total Bilirubin,albumin,alanine aminotransferase levels,pathological types,and postoperative abdominal complications(postoperative pancreatic fistula,postoperative biliary fistula,abdominal bleeding).This article uses SPSS 25.0 analysis software to analyze the data statistically.First,we use two independent sample t-tests for the measurement data between the two groups,and use the chi-square test for the count data between the two groups.Secondly,there were statistics for the appeal.Logisitic multivariate regression analysis was performed on the independent variables of the difference,and P <0.05 was regarded as significant,and finally the risk factors affecting the occurrence of DGE after PD were obtained.Results:According to the diagnostic criteria in this article,there are 18 patients(18/70)with DGE,and the incidence is about 25.7%,which is in line with literature reports.First,we found that the preoperative hemoglobin level(P=0.031),albumin level on the first day after surgery(P=0.009),and postoperative pancreatic fistula(P=0.043)were among the two groups.There are significant differences between.The analysis showed that compared with the non-DGE group,patients in the DGE group had lower preoperative hemoglobin levels and lower albumin levels on the first day after surgery,and had a higher incidence of postoperative pancreatic fistula.However,the two groups of patients were in gender,There was no statistical significance in preoperative total bilirubin level,operation duration,intraoperative blood loss,pathological type,etc(P>0.05).Second,we included the preoperative hemoglobin level,albumin level on the first postoperative day,and postoperative pancreatic fistula into the Logisitic multivariate regression analysis.The results showed that the albumin level on the first postoperative day(OR=0.790,P=0.045)is an independent risk factor for DGE after PD.Conclusion:DGE is one of the most common complications after PD.Although it is not fatal and can be cured by conservative treatment,it will increase the burden of personal and social health and economics,and bring great pain to patients and their families.This article retrospectively analyzed the clinical data of 70 PD patients from a single medical team of the Department of Hepatobiliary and Pancreatic Surgery of the First Hospital of Shanxi Medical University,and performed a statistical analysis.It can be seen that the preoperative hemoglobin level and postoperative pancreatic fistula are non-independent risk factors for DGE after PD.The albumin level on the first postoperative day is an independent risk factor for DGE after PD.