| Three techniques are studied to understand the impact on a sample after it traverses a turn using simulations from CFD−ACE+ and historical results. Plain turn studies are compared with results from an assumed linear electroosmotic flow profile across the channel and with a simulated step change in potential. Results show that CFD−ACE+ results are similar to previous studies and useful for modeling complicated transient scenarios. For the plain turn studies with small radii, CFD−ACE+ results show similar results to historical studies at high modified Peclet numbers, with a shift of the sample to the inner edge of the turn. For electroosmotic flow change, at high Peclet number, dispersion is correctable over short distances, with error of 10–20% for experimental and 4% for simulated results. A step change in potential adversely affects dispersion, but variance is beneficially affected. Recommendations for channel design are discussed, with a summary given. |
