| Objective:Through the administration of scraping intervention on pneumonic children,body temperature changes of these children after intervention were observed,and the immediate and continuous antipyretic effects of bladder scraping on children's pneumonia were further analyzed.At the same time,through the statistical analysis of endogenous pyrogenic content changes in children with pneumonia before and after treatment,the antipyretic mechanism of bladder scraping on pneumonic children was preliminarily discussed,so as to provide an experimental basis for its promotion for clinical treatment.Methods:A total of 100 subjects from the Inpatient and Outpatient Pediatric Department of Beijing University of Chinese Medicine's affiliated Dongfang Hospital,who met the inclusion criteria from July 2018 to June 2019,were enrolled into this study.They were randomly divided into the observation group and the control group with 50 cases each,with 14 subjects dropping out of this study.Finally,41 cases in the observation group and 45 cases in the control group were summarized and analyzed.The control group was administered conventional pneumonia treatment,which includes antibiotics and Traditional Chinese Medicine(TCM)herbal treatment,while the observation group was administered additional bladder meridian scraping treatment once,on top of conventional pneumonia treatment.Both groups of children have a complete body temperature-monitoring table and endogenous pyrogenic content test results.The results were statistically analyzed,and the immediate antipyretic effects of the control group as well as the continuous antipyretic effects of both groups were observed.Lastly,the endogenous pyrogenic content and the changes in CRP levels of both groups were compared.Results:(1)Immediate antipyretic efficacy:In the observation group,there were 41 study cases,and after treatment,there were 26 cases with obvious effects,accounting for 63.41%,14 cases with effects,accounting for 34.15%,and 1 case with no effects,accounting for 2.44%.(2)Continuous antipyretic efficacy:The area under the ROC curve of body temperature in the observation group was smaller than that of the control group(P<0.05).The frequency of use of antipyretic Western medication in the observation group was lower than that of the control group(P<0.05),so bladder meridian scraping could reduce the frequency of use of anti-pyretic Western medication in pneumonic children.The complete anti-pyretic time of the observation group was shorter than that of the control group(P<0.05),so scraping of the bladder meridian scraping could reduce the complete anti-pyretic time.There were 39 cases of complete antipyretic in the observation group,accounting for 45.35%,and 25 cases of complete antipyretic in the control group,accounting for 29.07%.The rate of complete antipyretic in the observation group was higher than that in the control group(P<0.05).(3)Endogenous pyrogenic content:There was no statistical difference in endogenous pyrogenic content between the two groups before treatment(P>0.05),i.e.they were at the same baseline with comparability.There was a decrease in endogenous pyrogenic content levels in both groups after treatment.(P<0.05).In addition,the levels of IL-1? and TNF-? in the observation group were lower than that in the control group(P<0.05)after treatment(P<0.05).There was no statistical difference in the levels of IL-6 and IFN-? between the two groups after treatment(P>0.05),so scraping of the bladder meridian can reduce thelevels of IL-1? and TNF-? in pneumonic children,but not the levels of IL-6 and IFN-?.(4)CRP:There was no statistical difference in CRP levels between both groups before treatment(P>0.05),with comparability.There was no statistical difference in CRP levels between both groups after treatment(P>0.05),and scraping of the bladder meridian did not reduce the CRP levels in pneumonic children.(5)Length of hospitalization:There was no statistical difference in terms of the length of hospitalization between both groups(P>0.05),and scraping of the bladder meridian did not shorten the length of hospitalization of pneumonic children.Conclusion:Scraping of the bladder meridian has a definite immediate antipyretic effect on pneumonia in children.Comprehensive analysis of the area under the ROC curve of body temperature,the frequency of use of antipyretic Western medication used,the duration and rate of complete antipyretic in both groups has shown that scraping of the bladder meridian has a definite continuous antipyretic efficacy.However,it did not reduce the CRP levels and shorten the length of hospitalization.Comprehensive analysis of changes in endogenous pyrogenic content changes in both groups suggests that the decrease in IL-1? and TNF-? levels might be the plausible antipyretic mechanism of bladder meridian scrapping for pediatric pneumonia. |
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