Based On Data Mining To Explore The Influence Of Traditional Chinese Medicine On Pregnancy In Patients With Endometriosis

Research purpose:Based on data mining technology,discuss the influence of traditional Chinese medicine on pregnancy in patients with endometriosis and the medication rules of Professor Zhao Ruihua.Research methods:This study collected and followed up the patients with endometriosis who were trying to get pregnant.Patients included in the outpatient clinic of Professor Zhao Ruihua,Department of Gynecology,Guang'anmen Hospital,China Academy of Chinese Medical Sciences from January 1,2014 to June 30,2019.Collected and organized patient data,followed up the patient's pregnancy through medical records and telephone follow-up,and conduct statistical analysisThis research was based on data from the Clinical Scientific Research Shared Data Acquisition System of Guanganmen Hospital,China Academy of Chinese Medical Sciences.According to the treatment cycle,it was divided into two periods before ovulation and after ovulation;according to syndrome differentiation,the patients were divided into cold coagulation and blood stasis,qi deficiency and blood stasis,qi stagnation and blood stasis,and phlegm-dampness stagnation.According to the different treatment after pregnancy,the prescriptions of patients were divided into tocolytic,difficulty of defecation after pregnancy,pregnancy cold,nausea during pregnancy.Professor Zhao Ruihua studies the rule of Chinese medicine for endometriosis in assisting pregnancy and relieving fetus,and explores the core prescriptions and their compatibility law.Research results:1.General situation:102 patients were included.2.Pregnancy:Follow-up up to 6 months after drug withdrawal,57 cases were pregnant,the total pregnancy rate was 55.88%,20 cases were pregnant with infertility,the pregnancy rate was 45.45%,and the median pregnancy time was 3 months.3.Professor Zhao Ruihua's core pulse and tongue based on syndrome differentiation:(1)The core pulse and tongue in the syndrome of cold coagulation and blood stasis are wiry thready pulse,pulse sinking and sliding,tongue dark red,tongue light red,moss thin white,moss white thick.(2)Thecore pulse and tongue in the syndrome of qi deficiency and blood stasis are wiry thready pulse,pale red tongue and thin white moss.(3)The core pulse and tongue in the syndrome of qi stagnation and blood stasis are wiry slippery pulse,tongue dark red,moss thin white.(4)The core pulse and tongue in phlegm-dampness stagnation are pulse sinking and sliding,pale and dark tongue,white and slightly thick moss.4.Professor Zhao Ruihua's core prescription analysis based on syndrome differentiation before ovulation prescription:(1)Cold coagulation blood stasis syndrome:fenugreek seeds,cassia twig,white peony root,glycyrrhiza,lanceolata,poria cocos,fried atractylodes,galli stomachichum corium,villous amomum,pogostemon cablin,ginger,jujube,etc.(2)Qi deficiency and blood stasis syndrome:lanceolata,tuckahoe,fried atractylodes,villous amomum,pogostemon cablin,galli stomachichum corium,Job's tears,glycyrrhiza,Chinese rose,medicated leaven,ginger,jujube,etc.(3)Qi stagnation blood stasis syndrome:bupleurum,white peony root,galli stomachichum corium,Job's tears,salviae,Chinese rose,lanceolata,poria cocos,fried atractylodes,glycyrrhiza,villous amomum,pogostemon cablin,cassia twig,ginger,jujube,etc.(4)Phlegm-dampness stagnation:bupleurum,pinellia,scutellaria,tuckahoe,angelica,ligusticum chuanxiong,white peony root,Chinese rose,cassia twig,villous amomum,pogostemon cablin,lanceolata,galli stomachichum corium,Job's tears,fried atractylodes,ginger,jujube,etc.5.Recipe analysis of prescription after ovulation:The prescription is based on the prescription before ovulation and supplemented with reinforcing Kidney Chinese medicine herbal.6.Professor Zhao Ruihua's core prescription analysis based on the four common diseases of pregnancy:(1)Tocolytic:lanceolata,tuckahoe,fried atractylodes,glycyrrhiza,villous amomum,ginger,jujube,wolfberry fruit,dodder,teasel root,ligustrum lucidum,etc.(2)Difficulty of defecation after pregnancy:lilium,Radix Glehniae,tuckahoe,fried atractylodes,glycyrrhiza,wolfberry fruit,dodder,ligustrum lucidum,etc.(3)Pregnancy cold:bupleurum,cassia twig,white peony root,scutellaria,lanceolata,tuckahoe,fried atractylodes,glycyrrhiza,ginger,jujube,villous amomum,etc.(4)Nausea during pregnancy:lanceolata,tuckahoe,fried atractylodes,glycyrrhiza,villous amomum,wolfberry fruit,dodder,teasel root,ligustrum luciduginger,ginger,jujube,lilium,etc.Research conclusions:1.Promoting pregnancy in patients with endometriosis,traditional Chinese medicine has played an important role.The pregnancy rate during medication is relatively high,and it is important to seize the first three months of treatment.2.Professor Zhao Ruihua's guidelines are based on disease differentiation,syndrome differentiation,and treatment by stages.The ideas for treating endometriosis include "staging before and after ovulation","type 4 syndrome differentiation" and "four common diseases after pregnancy",Pre-ovulation treatment is based on the four types of syndrome differentiation:cold coagulation and blood stasis,qi deficiency and blood stasis,qi stagnation and blood stasis,phlegm-dampness stagnation,and it is based on the care of the spleen and stomach.Solidifying the spleen and stomach is the basis of the treatment,and the conditioning of qi and blood is the core of the treatment.The prescription is based on the prescription before ovulation and supplemented with reinforcing Kidney Chinese medicine herbal.Pregnancy disease,tonic the spleen and kidney,regulate qi and blood,clinical attention should be paid to the treatment of disease and fetus.