Based On The Mismatched Negative Wave Of Auditory Event-related Potentials, This Paper Explores The Regulating Effect Of Mind-saving On Brain Processing

ObjectiveIn this study,the college students are used as the research object,and mind-keeping used as an intervention method which is basic of heart adjustment in qigong.Apply auditory event-related potential(AERP)technology to detect the state data of each stage.Observe the changing of the mismatch negative wave(MMN),and analyze the regulation effect of mind-keeping on the automatic information processing ability of college students' brains Provide scientific evidence for the experiment to make new ways for the intention to regulate the cognitive competence and prevent cognitive impairmentMethods72 undergraduates were recruited from the Beijing University of Chinese Medicine Dongfang College as subjects.who were randomly divided into a training group and a blank control group according to the ratio of 1:1.The training group was trained for 8 weeks in three phases,each of which included concentrated training and independent training,concentrated training was 5 times a week and 30 minutes each time;independent training was 6 times a week and 20minutes each time.The blank control group didn't participate in the training,only participated in the research evaluation process in parallel.The AERP measurement at two time point before and after the mind-keeping training.At both points,the subjects were required to perform normal life state(normal state 1),mind-keeping state and return-to-normal-life state(normal state 2).The test used oddball paradigm of psychology.Among them,the sound stimulation is a short pure tone with a duration of 100ms,the standard stimulation frequency is 1000Hz,and the deviation stimulation frequency is 2000Hz.The MMM amplitude and latency data of the subject are measured,and the brain regions were divided into frontal pole region<Fp1,Fp2>,frontal region<F3,F4,Fz>,frontal central junction region<FC3,FC4,FCz>,central region<C3,C4,Cz>,central parietal junction region<CP3,CP4,CPz>,parietal region<P3,P4,Pz>,temporoparietal junction region<TP7,TP8>,anterior temporal region<F7,F8>,middle temporal region<T3,T4>,posterior temporal region<T5,T6>,frontotemporal junction region<FT7,FT8>,occipital region<O1,02,Oz>.Analysis of variance for repeated measures design data for the mind-keeping training group and the blank control group.Pearson's correlation analysis was performed on the results of the main electrode points(frontal region<F3,F4>,central region<C3,C4>,parietal region<P3,P4>,temporal region<T3,T4>,occipital region<O1,O2>)in the left and right brain points of the mind-keeping groupResults1.Comparison of the amplitude of MMN in the two groups:(1)Trends within the group:?There was no statistical difference between the states of the training group before and after training.?The MMN amplitudes in both the parietal and temporoparietal junction regions of the blank control group were smaller than in normal state 2 than in normal state 1,resulting in statistically significant differences(P<0.05);the normal state 2 of the temporal parietal junction region in the post-training blank control group was also smaller than pre-training.volatility,with statistically significant differences in results(P<0.05);the normal state 1 in the middle temporal region in the post-training blank control group was smaller than pre-training,the results were statistically different(P<0.05).(2)Trends between the groups:There were no statistically significant differences between the two groups at each time point or state comparison(P>0.05)2.Comparison of the latency of MMN in the two groups:(1)Trends within the group:?In the training group:Post-training mind-keeping state compared with the normal statel in the central region,central parietal junction region,parietal region and frontotemporal junction region are shorter(P<0.05),and these trend continues in the central region,central parietal junction region,parietal region in normal state 2,with statistically significant differences in the results(P<0.05);post-training normal state 2 compared to normal state 1 in the frontal pole region,frontal region,frontal central junction region,and anterior temporal region are shorter(P<0.05),and normal state 2 with a shortened latency in the frontal region compared with mind-keeping state,the results were statistically different(P<0.05).?There was no statistical difference between the states of the blank control group before and after training.(2)Trends between the groups:there were no statistically significant differences between the two groups at each time point or state comparison(P>0.05)3.Left and right brain characteristics of the MMN before and after training in the training group:(1)MMN amplitude:Post-training significantly increased left-right brain correlations in central region,parietal region,and temporal region in the mind-keeping state;and there was an overall trend toward increased brain coordination in the frontal region and occipital region after training compared to the pre-training.(2)MMN latency:There was a tendency for left-right brain coordination in the frontal region,central region,and occipital region to decrease with state after training,and the minimal correlation in the mind-keeping state;temporal region showed increasing correlations with state change post-training,whereas parietal region showed the greatest correlations during mind-keeping state.ConclusionsMind-keeping can improve or maintain the excitability and involvement of brain neurons and avoid fatigue;it can reduce the automatic processing time of the brain for external stimuli and improve the efficiency of automatic information processing;it can stimulate the frontal region,parietal region,temporal region and central regions of the brain to collaborate and promote the higher regulation of somatic sensation and mental consciousness;to some extent,it can improve the correlation and coordination of the left and right brain.