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Clinical Observation Of The Prescription Of Buzhong Yiqi Huafang On Muscle Injury Caused By Statins

Posted on:2021-04-19Degree:MasterType:Thesis
Country:ChinaCandidate:Y T ShenFull Text:PDF
GTID:2434330614957723Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Purpose:To explore the effect of buzhongyiqi Decoction on the muscle injury caused by statins.To evaluate the clinical effect of buzhongyiqi Decoction in the treatment of muscle injury caused by statins,and to provide new ideas and methods for the clinical treatment of muscle injury caused by statins.Material and method:A total of 60 patients were selected.Vitamin D capsules were used for the treatment of the control group,Chinese medicine granules were used for the treatment of group 1,and the treatment group was given vitamin D capsules + Chinese medicine granules.To observe the changes of muscle strength grade,pain score and TCM syndrome score before and after treatment.Statistical methods SPSS26.0 statistical software was used to analyze the data.The measurement data in line with the normal distribution were presented by the t-test,and the count data were analyzed by the X2 test.Results:1.Improvement of muscle strength grading: compared with the treatment group before and after treatment,the muscle strength of the treatment group 1 and 2 improved(P1?P2<0.001),.change in muscle strength in the control group(P>0.001).After treatment,between the treatment group and the control group 1(P<0.001),differences between the treatment group and the control group 2(P<0.001).There was no difference in the treatment effect of vitamin D group before and after the comparison,and the treatment effect of traditional Chinese medicine granules and traditional Chinese medicine granules plus vitamin D group was better than that of vitamin D alone.There was no difference in the therapeutic effect between TCM granule and TCM granule plus vitamin D.In the control group,the clinical effective rates of western medicine in the treatment group 1 and 2 were 65%,85% and 85% respectively.2.Improvement of pain score: before and after treatment,the pain degree of treatment group 1and 2(P1?P2<0.001).pain was observed in the control group(P>0.001).After treatment,the treatment group and the control group 1(P<0.001),differences between the treatment group and the control group 2(P<0.001).There was no difference in the treatment effect of vitamin D group before and after the comparison,and the treatment effect of traditionalChinese medicine granules and traditional Chinese medicine granules plus vitamin D group was better than that of vitamin D alone.There was no difference in the therapeutic effect between TCM granule and TCM granule plus vitamin D.In the control group,the clinical effective rates of western medicine in the treatment group 1 and 2 were 65%,85% and 85%respectively.3.Changes in TCM syndrome score: before and after treatment,the scores of 1 and 2 in the treatment group decreased(P1?P2<0.001).The score of the control group(P>0.001).After treatment,the treatment group and the control group 1(P<0.001),the treatment group and and the control group 1(P<0.001),differences between the treatment group and the control group 2(P<0.001).There was no difference in the treatment effect of vitamin D group before and after the comparison,and the treatment effect of traditional Chinese medicine granules and traditional Chinese medicine granules plus vitamin D group was better than that of vitamin D alone.There was no difference in the therapeutic effect between TCM granule and TCM granule plus vitamin D.In the control group,the clinical effective rates of western medicine in the treatment group 1 and 2 were 60%,95% and 95% respectively.Changes in ck;before and after treatment,the pain degree of treatment group 1 and 2(P1?P2<0.001).pain was observed in the control group(P>0.001).After treatment,the treatment group and the control group 1(P<0.001),differences between the treatment group and the control group 2(P<0.001).There was no difference in the treatment effect of vitamin D group before and after the comparison,and the treatment effect of traditional Chinese medicine granules and traditional Chinese medicine granules plus vitamin D group was better than that of vitamin D alone.There was no difference in the therapeutic effect between TCM granule and TCM granule plus vitamin D.Conclusion:1.This study fully proved that the muscle discomfort caused by statins is located in the liver and spleen and is related to the small intestineand spleen and is related to the small intestine.Based on the physiological function of the liver,spleen and small intestine,the drug-induced injury is solid.2.The traditional Chinese medicine preparations with the treatment methods of strengthening spleen,soothing liver and detoxifying,and thickening intestine can promote the recovery ofmuscle discomfort,effectively improve the grading of muscle strength,relieve pain,and reduce the score of TCM syndrome,promote ck to return to normal.3.The effective treatment of muscle discomfort caused by statins can be achieved by supplementing the medium and benefiting the qi with no adverse reactions and non-toxic side effects.
Keywords/Search Tags:Statin, Muscle injury, Traditional Chinese Medicine, pain, weak
PDF Full Text Request
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