Correlation Analysis Of Anxiety And Depression In Maintenance Hemodialysis Patients With TCM Syndromes And Clinical Indicators

Objective:to analyze the distribution of anxiety-depression and TCM syndromes in maintenance hemodialysis patients,and the correlation between clinical indexes and anxiety-depression,so as to provide a new target for clinical treatment.Materials and methods:Cross-sectional epidemiological survey was used,using the Hamilton anxiety and depression scale(HAD)and the chronic kidney disease syndrome differentiation scale,73 patients undergoing maintenance hemodialysis in the blood purification center of Liaoning University of Traditional Chinese Medicine Hospital between December 2018 and December2019 were assessed,the patient’s HAD score and Tcm Syndrome were obtained Patients were also asked for general information(including name,dialysis age and access),and clinical indicators(including ALB(ALB),Hemoglobin(HB),Serum creatinine(SCR),Blood phosphorus(P),Blood calcium(CA),and Parathyroid hormone(Parathyroid hormone(PTH))were collected.SPSS22.0 was used to analyze the correlation between the degree of anxiety and depression in maintenance hemodialysis patients and TCM syndromes and clinical indexes.Results:1.The relationship between anxiety and depression scores of MHD patients and general data:The anxiety scores of MHD patients were affected by marital status,financial burden and complications(p < 0.05),the depression score was influenced by marital status,financial burden,complications and dialysis age(p < 0.05).The scores of anxiety and depression were not affected by gender and age(p > 0.05),and the scores of anxiety were not affected by dialysis age(p > 0.05).2.The relationship between anxiety and depression scores and clinical indexes in MHD patients: the anxiety scores in MHD patients were significantly correlated with the concentration of hemoglobin and the concentration of Alb(r-0.834,p < 0.05,r-0.744,p <0.05),there were significant differences in hemoglobin between mild anxiety,moderate anxiety and severe anxiety groups(p < 0.05),and there were significant differences in anxiety scores between severe anxiety and mild anxiety and moderate anxiety groups(p <0.05),and the differences between severe anxiety and mild anxiety and moderate anxiety were significant(p < 0.05),and the differences between severe anxiety and mild anxiety were significant(p < 0.05),there was a positive correlation between PTH and anxiety score in MHD patients(r 0.793,p < 0.05).There were significant differences in PTH between mild anxiety,moderate anxiety and severe anxiety groups(p < 0.05)There was significant difference between depression score and hemoglobin concentration and PTH in MHD patients,and there was negative correlation between depression score and hemoglobin concentration(r-0.558,p < 0.05),there were significant differences in hemoglobin values among the three groups(p < 0.05),and there was a positive correlation between PTH and Depression Score(r0.489,p < 0.05),there were significant differences in PTH between mild depression,moderate depression and severe depression(p < 0.05).3.The relationship between anxiety and depression score of MHD patients and Tcm Syndrome: The distribution of deficiency of Qi and Yin Syndrome in Tcm Syndrome:deficiency of spleen and Kidney Yang Syndrome > deficiency of spleen and Kidney Qi Syndrome > deficiency of Yin and Yang Syndrome > deficiency of liver and Kidney Yin Syndrome.The distribution of Standard Syndrome: Blood Stasis Syndrome > Damp-turbidity Syndrome / damp-heat Syndrome > Wind-dryness Syndrome > Heat-toxin Syndrome.The anxiety and depression of MHD patients were different in different TCM syndromes: the Anxiety Syndrome of deficiency of Qi and Yin and deficiency of spleen and Kidney Yang were more serious,there were differences in anxiety scores between qi-yin Deficiency Syndrome and spleen-kidney Qi Deficiency Syndrome,liver-kidney Yin Deficiency Syndrome and yin-yang deficiency syndrome(p < 0.05),and between spleen-kidney Yang Deficiency Syndrome and spleen-kidney Qi Deficiency Syndrome and yin-yang deficiency syndrome(p < 0.05)The degree of the syndrome of blood stasis and damp-heat was more serious in the syndrome of depression,and the scores of the syndrome of blood stasis were different from the syndrome of damp-turbidity,the syndrome of wind-dryness and the syndrome of heat-poison(p < 0.05)There were significant differences in depression scores between damp-heat syndrome and damp-turbidity syndrome,wind-dryness syndrome and heat-toxin syndrome(p < 0.05).Conclusion:1.The marital status,financial burden and complication number of MHD patients were related to anxiety score,and the marital status,financial burden,complication and Dialysis Age were related to depression score.The degree of financial burden and the number of complications were positively correlated with the degree of anxiety and depression,the length of dialysis age was positively correlated with depression score,and the anxiety and depression score of single patients was higher than that of married ones.2.Hemoglobin,ALB and PTH were correlated with anxiety and depression in MHD patients.Hemoglobin was negatively correlated with the degree of anxiety and depression,ALB was negatively correlated with anxiety score,and PTH was positively correlated with the degree of anxiety and depression.3.The relationship between TCM syndromes and anxiety-depression in MHD patients,the degree of deficiency of both Qi and Yin and deficiency of spleen and kidney-yang were more serious in anxiety syndrome,and blood stasis syndrome and damp-heat syndrome were more serious in depression syndrome.