Correlation Analysis Between TCM Syndromes And C-reactive Protein And Blood Lipids For Recurring Angina Pectoris After PCI

Purpose:To explore the correlation between TCM syndrome types,C-reactive protein and blood lipid in patients with recurrent angina after PCI,and the clinical significance of two laboratory indexes in patients with recurrent angina after PCI,so as to seek objective quantitative indexes for TCM syndrome differentiation of recurrent angina after PCI and provide new ideas for clinical medical students.Material and method:From May 2018 to may 2019,168 patients from the Department of Cardiology,Affiliated Hospital of Liaoning University of traditional Chinese medicine,who were diagnosed as recurrent angina after PCI,were selected as the study objects,including 118 males and 50 females;the age was 89 years old at the maximum and 28 years at the minimum,with an average age of 62.98 ± 11.60 years.According to the dialectical classification of the patients on the day of admission,there were 68 cases of phlegm stagnation and blood stasis,56 cases of qi deficiency and blood stasis,21 cases of qi stagnation and blood stasis,13 cases of Qi Yin deficiency and 10 cases of Yang Qi deficiency and decline.All the participants need to exclude the patients with chest pain caused by non heart disease,recent acute infection,severe trauma,severe liver and kidney dysfunction,other drug study patients and heart failure patients within 3 months.The general clinical data of the selected patients were recorded,including age,gender,smoking history,drinking history,etc.,and the patients were treated with TCM syndrome differentiation.According to the TCM diagnosis standard,the final syndrome differentiation was determined by two main TCM doctors,which were divided into five syndrome types: Qi deficiency and blood stasis group,qi stagnation and blood stasis group,phlegm turbidity and blood stasis group,Qi Yin deficiency and yang qi deficiency and failure group Group.After admission,the patient immediately took C-reactive protein,blood routine,renal function,fasting or the next morning to collect venous blood to test liver function,blood lipid series,etc.All the selected patients were graded for angina pectoris and the total score of angina symptoms was evaluated.The correlation of LDL-C and CRP in each group was compared with the results of laboratory examination,and spss24.0 was used for statistical analysis.Results: 1.In 168 patients with angina pectoris after PCI,the highest frequency of phlegm and blood stasis was 68 times(40.5%),followed by 56 times(33.3%),21 times(12.5%),13 times(7.7%)and 10 times(6.0%).Phlegm turbid blood stasis syndrome,Qi deficiency blood stasis syndrome and qi stagnation blood stasis syndrome are the main syndromes of recurrent angina after PCI.2.The distribution characteristics of male TCM syndrome types: phlegm turbid and blood stasis syndrome > Qi deficiency and blood stasis syndrome > qi stagnation and blood stasis syndrome > Yang Qi deficiency and decline > Qi Yin two deficiency syndrome;female TCM syndrome types: Qi deficiency and blood stasis syndrome > phlegm turbid and blood stasis syndrome > Qi Yin two deficiency syndrome > qi stagnation and blood stasis syndrome > Yang Qi deficiency and decline.There was a significant difference in gender between Qi stagnation and blood stasis syndrome(P < 0.05).3.Compared with the age level of TCM syndrome types,Qi Yin deficiency syndrome > Qi deficiency and blood stasis syndrome > Yang Qi deficiency and decline syndrome > qi stagnation and blood stasis syndrome > phlegm turbid and blood stasis syndrome.There was significant statistical significance in the comparison of phlegm and blood stasis syndrome,Qi and yin deficiency syndrome and Qi deficiency and blood stasis syndrome with age(P < 0.05);there was significant statistical significance in the comparison of Qi and yin deficiency syndrome,qi stagnation and blood stasis syndrome with age(P < 0.05).4.The difference of LDL-C between different TCM syndrome types is different.There is a statistical difference between phlegm and blood stasis syndrome and Qi deficiency and blood stasis syndrome(P < 0.05),and the LDL-C level of phlegm and blood stasis syndrome is higher than that of qi stagnation and blood stasis syndrome.5.The difference of CRP between different TCM syndromes was different,and there was statistical difference between Qi deficiency and blood stasis syndrome and qi stagnation and blood stasis syndrome(P < 0.05).6.The difference of angina score between different TCM syndromes was different.There was significant difference between phlegm turbid blood stasis syndrome and Qi deficiency blood stasis syndrome(P < 0.05).7.The levels of smoking history,drinking history,TC,TG and HDL-C were not statistically significant(P > 0.05).Conclusion: 1.The TCM Syndromes of angina after PCI were mainly phlegm and blood stasis,qi stagnation and blood stasis,and Qi deficiency and blood stasis.2.After PCI,the scores of LDL-C and CRP were different in different TCM syndromes.The level of LDL-C and CRP was higher in phlegm turbid and blood stasis syndrome,and the score of angina symptom scale was higher.The clinical symptoms of recurrent angina were obvious.3.LDL-C and C-reactive protein have significant correlation with recurrent angina after PCI,which have certain advantages in the evaluation and prognosis of recurrent angina after PCI.