| Objective: To observe and analyze the efficacy of Chinese medicine in the treatment of cancer related fatigue and explore the common prescription of Chinese medicine in the treatment of cancer related fatigue.Methods:Query by electronic medical record system in liaoning university of traditional Chinese medicine affiliated hospital oncology in October 2017 to October 2018,a total of 478 patients with malignant tumor diagnosis standard and(same person over and over again in the hospital is in 1 case),selected in this study,discharge standard of patients with cancer related fatigue pixu(spleen deficient)120 cases,70 cases of patients with oral Chinese medicine medicinal broth fatigue as Chinese traditional medicine group,50 patients not taking Chinese traditional medicine medicinal broth of fatigue as the Chinese medicine group.Treatment of traditional Chinese medicine group is a regular treatment,Chinese medicine treatment group patients in the treatment of general + one oral Chinese medicine treatment,extraction of patient information into the Excel table,analysis of the commonly used prescription of traditional Chinese medicine treatment group,and will improve symptoms in patients with fatigue,cancer patients quality of life score and TCM symptom scores,and related laboratory results as analysis indicators,to make the data statistics processing,evaluation of curative effect before and after treatment.Results:1.Traditional Chinese medicine of traditional Chinese medicine group were statistically concluded that drug use frequency is greater than 5 times of 69,which USES frequency from high to low arrangement are the top ten main licorice,pseudostellaria root,tuckahoe,atractylodes,radix astragali,coix seed,pinellia,zhejiang fritillary,spreading hedyotis herb,barbed skullcap herb,radix pseudostellariae,poria cocos,atractylodes,present frequency during the four main licorice herbs at the same time for 39 times,accounted for 55.71% is sijunzi soup or derivative square at the heart of the drug.2.Comparison of fatigue efficacy: there were 70 cases in the TCM group,37 cases were effective in treatment,8 cases were cured,and 25 cases were ineffective,with a total effective rate of 64.28%.In the 50 cases in the non-tcm group,14 cases were effective in treatment,3cases were cured,and 33 cases were ineffective,with a total effective rate of 34.00%.3.Comparison of TCM syndrome efficacy: the effective rate of the TCM group was 44.28%,and that of the non-tcm group was 24%,P<0.05 was significant.The syndrome score of both groups was reduced,and the reduction of syndrome score in the TCM group was significantly different from that in the non-tcm group,with statistical significance.4.Comparison of physical condition improvement: KPS score of patients in the TCM group was significantly increased compared with that before medication,while that in the non-tcm group was not significantly increased;ZPS score of patients in the TCM group was significantly increased compared with that before medication,while ZPS score of patients in the non-tcm group was slightly increased compared with that before medication.5.Comparison of weight improvement: patients in the traditional Chinese medicine group gained weight significantly after treatment,while patients in the non-traditional Chinese medicine group lost weight slightly after treatment.There was a significant difference in weight after treatment between the two groups(P<0.05).6.Comparison of improvement of laboratory indicators: pairwise comparison of various laboratory examination indicators of patients in the two groups showed that the test results were all P > 0.05,with no statistical significance.Conclusion:1.Sijunzi decoction is the most commonly used prescription for clinical treatment of spleen deficiency type CRF,on the basis of which syndrome differentiation is added or reduced.2.TCM decoction can significantly improve the fatigue symptoms of CRF patients.3.TCM decoction can improve clinical symptoms and reduce TCM syndrome integral.4.TCM decoction can effectively improve the physical condition of patients,improve the KPS score and reduce the ZPS score.5..Chinese medicine decoction can effectively increase patients' weight and improve their nutritional status.6.The efficacy of the two groups was equal in improving laboratory indicators. |
PDF Full Text Request