A Retrospective Clinical Study Of 366 Hospitalized Patients With Eczema

Purpose:Clinical data of 366 hospitalized patients with eczema in dermatology were collected and retrospectively studied to explore the characteristics of clinical data,distribution characteristics of rash and the relationship between various syndromes and related factors,so as to provide new ideas for clinical guidance.Data and Method:the clinical data of 366 eczema patients who were hospitalized at the dermatology department of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from 2017-9-23 to 2018-9-22 and who met the inclusion criteria was collected and studied.Their general conditions(such as gender,age,occupation,etc.),disease-related factors(such as the onset season,course of disease,living habits,history of allergies,rash sites,etc.),severity of skin lesions and related laboratory test indexes were summarized,and the study data was entered into an Excel spreadsheet and statistically analyzed using IBM SPSS 22.0 statistical software.Results:1.General data: Among 366 patients,there were 206 males(56.3%)and 160 females(43.7%);aged at 19-89 years-old,with a mean age of 58.44±15.18 years old,of which the patients who aged from 50-69 years old accounted for the largest percentage;The course of disease lasted 3days minimally,and 30 years maximally,the average duration of disease was 42.4±64.7months.The average disease course duration of patients with blood deficiency and wind dryness was the longest,the average disease course was 91.91±102.89 months;the length of stay was 6 days minimally,and 18 days maximally,the average length of stay was 12.8 ± 2.5days.2.Disease-related factors: The incidence of eczema was the highest in summer,which was106 cases(30.1%)and lowest in winter,which was 71 cases(19.3%).The incidence of disease was the highest in the solar terms like summer solstice and Limit of Heat.In general,the incident number was concentrated in spring and summer,but no difference between the syndrome types.The affected population was mostly the emeritus and retired;there were 116 cases of patient with smoking history,138 cases of patient with drinking history,and most ofthem were male;there were 23 cases of patient with allergic diseases,and 86 cases of patient with history of allergy;the allergic drugs were commonly streptomycin,sulfonamides,Cephalosporin.3.TCM syndrome types and related factors: Inhaled type allergen is higher in positive rate than the ingestive type allergen,but there is no difference in syndrome type;there is a difference between total cholesterol and syndrome type,and the total cholesterol value of patients with blood deficiency and wind dryness is lower than other syndromes;There is a difference between triglyceride and CRP and syndrome type.The value of triglyceride in patients with blood deficiency and wind dryness is lower than other syndrome types.The CRP value of patients with spleen deficiency and dampness type is lower than that of the patients with damp heat accumulation type;there is an obvious difference in the degree of itchiness between all syndrome types before treatment.The patients of spleen dampness and wetness type,as compared with the other two syndrome types,had a lower degree of itching;there is a significant difference in the degree of skin lesions before treatment between all syndrome types,and the degree of skin lesion of the patients with blood deficiency and wind dryness was lower than the other two syndrome types.4.Others: The proportion of patients with dampness and heat accumulation was the highest,which was 193 cases(52.7%);the skin lesions were most likely to occur at the limbs and trunk;after treatment,the itching and skin lesion scores were significantly lower than before.Conclusion:1.In this study,the pathogenic factors of eczema are related to total IgE,immune function,blood lipid and so on.2.This study found that among the quick-onset allergens,damp-heat skin-accumulating type was sensitive to wheat and dust mites,spleen-deficiency and damp-accumulating type was sensitive to Artemisia argyi,cockroaches and dust mites,blood-deficiency and wind-drying type was sensitive to elm,cockroaches and dust mites,while in delayed-onset allergens,damp-heat skin-accumulating type was sensitive to milk,eggs,wheat,soybeans,cod,spleen-deficiency and damp-accumulating type and blood-deficiency and wind-drying type were sensitive to eggs and wheat.3.After treatment,the patient's symptoms and signs were improved.In terms of reducing EASI score,the dryness type of blood deficiency was better than other syndromes.In reducing pruritus degree score,spleen deficiency wet accumulation type is better than other syndromes.4.Integrated traditional Chinese and western medicine treatment of eczema,the effect is significant,the treatment of spleen deficiency wet accumulation eczema show high efficiency.