| Objective:By analyzing the medical records of 119 inpatients diagnosed as acute eczema or acute onset of chronic eczema,who were diagnosed as dampness-heat skin type eczema according to TCM syndrome differentiation,we collected the characteristics,influencing factors,TCM and Western medicine treatment and other data of patients with dampness-heat skin type eczema,so as to provide reference for clinical treatment of this disease.Materials and Methods:A total of 119 patients with acute eczema or acute onset of chronic eczema,who were hospitalized in the dermatology ward of Fengtian Hospital of Traditional Chinese Medicine on September 1,2016 and with TCM syndrome differentiation of moist and heat skin type eczema,were collected.The basic data(gender,age,course of disease,length of stay,disease history),disease-related factors(onset season,history of bad habits,etc.),allergy history,skin lesions,laboratory examination,EASI score,VAS score,syndrome score at admission,and treatment of traditional Chinese and western medicine were summarized.Cooperated to expound the thinking of traditional Chinese medicine decoction and other methods in the treatment of dampness-heat skin type eczema,and used statistical software for processing,and analyzed and obtained the conclusion.Results:1.General information:119 inpatients with skin-hot and damp-skin eczema with complete medical records were included in this study,including 59 males and 60 females,with a male to female ratio of 0.98:1.There was no significant difference in the incidence of this disease between males and females(P>0.05).The mean age of the 119 patients was 49.82±17.15years,40.00±11.72 years in the non-elderly group and 68.51±7.58 years in the elderly group.In terms of course of disease,the average course of disease was 44.75±66.18 months in 119patients,66.49±80.51 months in the elderly group and 33.32±54.42 months in the non-elderly group.The course of disease in the elderly group was significantly longer than that in the non-elderly group(P<0.05).The average hospitalization time of 119 patients was 14.71±3.76 days.Of the 119 inpatients,46(38.66%)had the first disease and 73(61.34%)had the recurrence.2.The onset season and solar terms:patients generally onset in spring and summer seasons,the major heat and Grain Rain in the majority of solar terms.3.History of allergy:Among the 119 patients,21 patients(17.65%)had a history of drug allergy,while 98 patients(82.35%)denied any history of allergy.4.History of bad habits:Among the 119 patients,there were 18 patients with history of bad habits,including 16 males and 2 females.5.Disease history:the elderly group was more likely to have other diseases than the non-elderly group(X~2=16.48,P<0.01).6.Laboratory tests:The Ig E abnormality rate in the elderly group was significantly higher than that in the non-elderly group.Special allergen:The positive rate of special allergen food group and inhalation group was significantly higher in the elderly group than in the non-elderly group.7.Skin lesions:erythema was the most common manifestation of patients(116 cases,97.48%),followed by papules(113 cases,94.96%),and exudation(112 cases,94.12%).8.TCM treatment:The number of patients who used TCM methods are:TCM decoction(119cases,100%),bloodletting therapy(81 cases,68.07%),acupuncture(80 cases,67.23%),and Chinese medicine decoction(67.23%)75 cases,63.03%).Among them,the top ten Chinese medicine decoctions are:Seed of Asiatic plantain,Honeysuckle,Radix Paeoniae Rubra,Cortex Moutan,Dried rehmannia root,Radix scrophulariae,Smilax glabra,Smilax china,Chuanmutong,Alisma orientalis.The frequency of drug pairs,from high to low,the first four pairs are:Radix Paeoniae Rubra-Cortex Moutan(97 times),Dried rehmannia root-Radix Scrophulariae(94 times),Smilax glabra-Smilax China(83 times),Chuanmutong-plantain seed(67 times).9.Western medicine treatment:117 cases(98.32%)of the 119 patients were treated with intravenous drugs.62 cases(52.10%)received antihistamines orally,and 57 cases(47.90%)did not receive antihistamines orally.10.Efficacy evaluation:Among 119 patients,1 case was cured,29 cases showed obvious effect,87 cases were effective,and 2 cases were ineffective,with a total effective rate of98.32%.The VAS score of 119 patients was 75.88±5.88 points before treatment and 13.11±8.21 points after treatment.VAS pruritus score was significantly decreased before and after treatment(P<0.05).Before treatment,the EASI score of 119 patients was 24.18±5.91,and after treatment,the EASI score was 10.68±3.28.EASI scores of 119 patients were significantly decreased before and after treatment(P<0.05).Syndrome score:The symptom score and the overall syndrome score were significantly decreased before and after treatment(P<0.05).Conclusion:1.This study showed that the abnormal rate of total Ig E in serum was higher in the elderly group and the disease course was relatively long.2.The study showed that the top four use frequencies of traditional Chinese medicine for the treatment of dampness and heat skin type eczema were:Radix Paeoniae Rubra-Cortex Moutan(97 times),Dried rehmannia root-Radix Scrophulariae(94 times),Smilax glabra-Smilax China(83 times),Chuanmutong-plantain seed(67 times).3.In this study,it was found that the main principle for the treatment of dampness and heat skin type eczema is"clearing heat and cooling blood,detoxifying clearing damp"method.(1) Clearing heat and cooling blood:It is often manifested as redness of skin lesions and obvious burning sensation.Drugs such as red peony root,peony bark,raw soil and root root,etc.(2)clearing damp:detoxification is often characterized by skin redness,seepage,drugs such as glabrous greenbrier rhizome,smilax,armand clematis,plantain seed,rhizoma alismatis,honeysuckle,etc. |
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