Discussion On The Clinical Features Of Wenrun Xinjinpei Principle In Treating Bronchial Asthma With Yang Deficiency In Chronic Persistent Period

Background:Chronic persistence is in the transitional stage of asthma attack.It is considered to be the golden period of asthma treatment.The body has not yet recovered to its optimal state.Good control can be turned into clinical remission,and poor control into acute exacerbation.Therefore,treatment is particularly important at this time.Many chronic persistent asthma patients were found to have symptoms such as cough,wheezing,chest tightness,cold limbs,weak waist and knee,frequent night urine deficiency.These symptoms also directly affect the quality of life of patients in daily life.This article mainly studies this clinical phenomenon.The first part of this article reviews the clinical research status of Western Medicine on chronic persistence of bronchial asthma.The second part reviews the main research ideas of modern Chinese medicine on chronic persistence of asthma.The second part collects clinical case data and uses retrospective study to explore the clinical characteristics of chronic persistence of bronchial asthma.It was found that the main syndromes of asthma in this period were deficiency of lung and spleen qi and deficiency of lung and kidney yang.Methods:1000 hospitalized patients with bronchial asthma and complete lung function records were collected in the medical record room before December 31,2018.From December 2015 to December 2018,two hospitalized cases of Chinese medicine pulmonary disease and cases in the study of Chinese medicine intervention program were collected.The Pearson correlation is used for clustering parameters(similarity coefficients between classes),and the observation indexes are standardized by 0-1 full distance.Posson regression analysis was used for regression analysis,with P<0.05 as the statistical significance.Results:1.Based on the clustering results,the main symptoms of chronic persistence of bronchial asthma can be divided into two categories:the first type:fatigue,shortness of breath,dizziness,wheezing,frequent nocturnal urination,sweating;the second type:abdominal distention,lumbar and knee weakness,cold limbs,cough and dementia.Referring to the syndrome differentiation standards provided by Diagnostics of Traditional Chinese Medicine(edited by Ji Shaoling)and Diagnostic Criteria of TCM Syndromes of Bronchial Asthma(2016 edition),it can be classified into two types of syndrome groups,the first can be classified as "Lung-Kidney Qi Deficiency",the second is "Spleen-Kidney Yang Deficiency";the second is to classify "Lung-Qi Deficiency"and"Spleen-Kidney Yang Deficiency" into the broad category of Yang Deficiency for further analysis.There are many symptoms of Yang deficiency syndrome in clinic.Considering the convenience of operation and counting,the number of nocturnal urine was selected as the object of observation.Pearson correlation analysis was used to observe the correlation between nocturnal polyuria and Yang deficiency syndrome.The results showed that nocturia was correlated with Yang deficiency syndrome(P<0.05).3.P oisson regression analysis of nocturia frequency showed that gender,age and asthma control level had an effect on nocturia frequency in patients with bronchial asthma.Specifically,after controlling age and asthma level,the risk of nocturia frequency in women was 0.4396 times higher than that in men(exp(-0.4396)=0.64 times).The risk of nocturnal urination per unit of age was 1.03 times higher than exp(0.0250)=1.03 times higher than that of the previous unit.After controlling sex and age,the risk of nocturnal urination per unit of asthma control was 1.43 times higher than that of exp(0.3593)=1.43 times of that of the previous unit.Discussions:1.Ben(Yang)deficiency syndrome is an important clinical feature of chronic persistence of bronchial asthma.Although lung,spleen and kidney have their own characteristics of change in this period,the syndrome of Qi deficiency and Yang deficiency are often miscellaneous and miscellaneous;2.The frequency of nocturia reflects the functional relationship of viscera in chronic persistence of bronchial asthma;3.Analysis of a typical case.