Clinical Study Of Cognitive Behavior Therapy For Insomnia Combined With Shugananshen Decoction On Insomnia With The Pattern Of Depressed Liver QI Transforming Into Fire

Objective: To observe the clinical efficacy of Cognitive Behavior Therapy for Insomnia(CBT-I)combined with Shugananshen Decoction on insomnia with the pattern of depressed liver qi transforming into fire in the treatment.Methods: Ninety-six patients with insomnia were divided into three groups.The study group(CBT-I + Shugananshen Decoction)includes a total of 32 subjects.The study group and the control group A were double-blind,and control group B was single-blind.The control group A(CBT-I + the placebo)includes a total of 32 subjects.The control group B(single Shugananshen Decoction)includes a total of 32 subjects.In the study,one dose of Shugananshen Decoction was given daily,and 42 doses were given totally.CBT-I was given at the same time as taking medicine.The control group A was given a placebo once a day,and placebo was given as a dose of 1/10 which in the study group.CBT-I was given at the same time as taking medicine.The control group B was given one dose of Shugananshen Decoction daily.Taking medicine was given general psychological support treatment instead of CBT-I system treatment.Three groups of patients were followed up every 2 weeks for 6 weeks.The Modified SPIEGEL Scale,the Pittsburgh Sleep Quality Index,Insomnia with the pattern of depressed liver qi transforming into fire score scale,and the Dysfunctional Beliefs and Attitudes about Sleep Scale were used for comparison before and after treatment.Results: A total of 96 patients with insomnia were enrolled,and 91 patients were completed,including 30 in the study group,31 in the control group,and 30 in the control group B.1.PSQI: After comparison between groups,the decrease of study group and the control group B were higher than that of the control group A(P<0.05).There were differences in the study group,control group A and control group B at different weeks(P<0.05).The three groups showed the scores that 6 weeks<4 weeks<2 weeks<0 weeks(P<0.05).The Modified SPIEGEL Scale: After comparison between groups,the study group and the control group B were lower than that of the control group A(P<0.05).There were differences in the scores of the study group,the control group A and the control group B at different weeks(P<0.05).The scores of the study group and the control group A showed the scores that 6 weeks<4 weeks<2 weeks<0 weeks(P<0.05).There were differences between the two weeks except for the 4th and 6th weeks of the control group B(P<0.05).2.Efficacy evaluation: the total effective rate of the study group was 90.00%,the total effective rate of the control group A was 58.06%,and the total effective rate of the control group B was 80.00%.The total effective rate of the study group was better than that of the control group A(P<0.05),there was no significant difference between the study group and the control group B.3.Insomnia with the pattern of depressed liver qi transforming into fire score scale: Compared between groups,the scores of the control group A was significantly larger than the study group and the control group B(P<0.05).There were differences in the scores of the study group,the control group A and the control group B at different weeks(P<0.05).The study group and the control group B showed the scores that 6 weeks<4 weeks<2 weeks<0 weeks(P<0.05).There were differences between the two weeks except for the 2nd and 4th weeks of the control group A(P<0.05).4.DBAS-16: The comparison between the study group and the control group A was significantly lower than that before treatment(P<0.05)..Conclusion: 1.Cognitive Behavior Therapy for Insomnia combined with Shugananshen Decoction has good curative effect on insomnia.Its curative effect is similar to that of single Shugananshen Decoction and is superior to Cognitive Behavior Therapy for Insomnia alone.2.Shugananshen Decoction can improve the patient's symptoms of pattern of depressed liver qi transforming into fire by comparing Cognitive Behavioral Therapy for Insomnia.3.Cognitive Behavior Therapy for Insomnia can correct wrong sleep cognition and establish a good sleep belief in patients with insomnia.4.Cognitive Behavior Therapy for Insomnia combined with Shugananshen Decoction in the treatment of insomnia compliance and safety,no significant adverse events were observed during the treatment.