Professor Yu Xiaoping's Experience In Treatment Of Chronic Cough Based On Data Analysis

Objective: By collecting,sorting out and analyzing the medical records of Professor Yu Xiaoping in the treatment of chronic cough,this paper summarizes Professor Yu Xiaoping's medication rules and academic thoughts in the treatment of chronic cough.By collecting,sorting out and analyzing the medical records of Professor Yu Xiaoping in the treatment of chronic cough,this paper summarizes Professor Yu Xiaoping's medication rules and academic thoughts in the treatment of chronic cough.Method: Collect the medical records of chronic cough diagnosed and treated by Professor Yu Xiaoping from August 2016 to February 2019,and bring the medical records that meet the inclusion criteria into this study.The data of medical records included in the study were input into the database of "Traditional Chinese Medicine Inheritance Assistant Platform" of TCM after standardized processing,and the data were checked after input to ensure accuracy.Through data mining and statistical analysis of data in the database by TCM Assistant Traditional Platform and Microsoft Excel system,Professor Yu Xiaoping's experience in the diagnosis and treatment of chronic cough was summarized by combining the data mining results with clinical practice.Results:1.108 patients with chronic cough were included in this study.There were 219 medical records and 219 prescriptions.The ratio of male to female was 1:1.84,and most of the patients were in the age range of 40-49 years.In medical cases,the diagnosis of upper airway cough syndrome(37.9%)was common in Western medicine,followed by cough variant asthma(33.3%).The syndrome types of traditional Chinese medicine were mainly wind-induced lung syndrome(28.7%)and wind-heat-induced lung syndrome(26%)and wind-induced lung syndrome(67.4%).2.In medical records,cough and sputum(28%)were the main clinical symptoms,with moderate cough(45.2%)as the main symptoms and dry cough(39.7%)as the main symptoms.The symptoms conformed to the objective clinical law.3.Except cough and expectoration,the other symptoms in medical records can be divided into seven groups: symptoms expressed by disease location,symptomsexpressed by the nature of sputum,symptoms expressed by stimulating inducements,symptoms expressed by other viscera,symptoms of general situation and symptoms without classification.Among them,the symptoms described by location accounted for the most(23.3%)and spleen and stomach symptoms(4.6%)were the most common.4.The prescription medication in medical records involves 160 flavors,and the four Qis of drugs are mainly cold,warm and calm(92.4%).Among them,cold drugs are the most frequently used(48.6%)and warm drugs(21.9%).The five flavors of drugs are bitter,bitter and sweet(89%)and bitter drugs(37.4%)and bitter drugs(31.5%).The meridians of drugs are mainly attributable to the lungs,liver and stomach(58.4%).5.Medical records involved 32 kinds of high-frequency medication(76.2% of the total medication),which belonged to nine major medicines,among which phlegm-resolving cough and Asthma-relieving drugs were the most frequently used(accounting for 22.5%of the total medication).In phlegm,cough and asthma relief,Qi-regulating,cough-relieving and Asthma-relieving drugs were the most common(accounting for9.2% of the total drug use).High-frequency medication involves 18 kinds of efficacy,mainly dispelling wind effect drugs(18%),followed by eliminating wind effect drugs(25.5%)and promoting dispersing effect drugs(19.8%).6.154 cases(70.3%)were treated with insecticides.7.According to the statistical results and prescription rules,through the frequency and confidence statistics,common drug combinations were obtained: Aster-Fabricius,Platycodon grandiflorum-Aurantium fructus,Cicada ecdysis-Bombyx mori,Salvia Miltiorrhiza-Tulip,Coptis-Evodia rutaecarpa-Corrugated Zi,Scutellaria-Zhuli Banxia,Bupleurum-Qianhu.8.Through the network-based correlation analysis,the core prescriptions used in the case of chronic cough are: shooting dry,cicada slough,silkworm,Qianhu,Bupleurum chinense,Scutellaria baicalensis,Pinellia ternata,aster,tuber,Platycodon grandiflorum,aurantium fructus,Salvia miltiorrhiza,liquorice,Coptis chinensis,Evodia rutaecarpa,corrugated.Conclusions:1.Professor Yu believes that the main cause of chronic cough is "wind evil loves lung",which combines wind,phlegm and blood stasis to block lung qi.Therefore,Professor Shangyu takes expelling wind and relieving cough as the main treatment principle,and combines insect drugs to search for wind and remove collaterals,clear lung and removephlegm,regulate qi and promote blood circulation,so as to eliminate wind evil and eliminate phlegm and blood stasis at the same time.2.Yu Shi pays attention to the treatment of chronic cough by differentiating the location of the disease,and insists on the combination of Xuansu and Jiangsu,cold and warm,and cold.In addition,attention should also be paid to protecting the spleen and stomach,using Coptis chinensis-Evodia rutaecarpa-corrugated fruit and shellfish as empirical medicines.3.Based on data mining and clinical experience,it is concluded that "shooting dry,cicada slough,silkworm,Qianhu,Bupleurum,Scutellaria baicalensis,Pinellia ternata,Aster,Bupleurum fargesii,Platycodon grandiflorum,Fructus Aurantii,Salvia Miltiorrhiza,Tulip,Coptis,Fructus Evodiae and Corrugated Fructus" are the basic prescriptions for Yu Shi's treatment of chronic cough.4.This study did not analyze the relationship between symptoms,changes in severity of illness and dosage of drugs.Further studies should be carried out in the follow-up study.