Study On The Health Effects Of Climate Factors And Heavily Polluted Weather On Children With Asthma

Objective: Analyzes the impact of climate factors and heavy pollution weather on children with asthma,and provide further comprehensive and objective basis for the prevention and treatment of asthma.Methods: Twenty-five asthmatic children and twenty-five healthy children were selected from our hospital.Record basic data(age,gender,BMI),risk factors(including birth history,feeding history,past allergy history,past recurrent pneumonia history,family allergy and asthma history),acute trigger factors(including respiratory infections,Climate change,irritating food,no obvious inducement,strenuous exercise,air pollution,irritating gas),clinical symptoms and signs,peripheral blood eosinophil count,peripheral serum inflammatory factors(Ig-E,IL-4),lung function(FEV1,FEV1 \ FVC,PEF),child asthma control questionnaire(C-ACT),and other parameters,using statistical methods scientifically Comprehensive analysis of indicators.Results: There was no difference in the basic data of children in the asthma group and the control group(P?0.05);the ratio of past allergies and family allergies and / or asthma history in the asthma group was significantly higher than that in the control group,and the difference was statistically significant,(P?0.05);Ranking of the causes of acute asthma attacks: respiratory infections,climate change,eating irritating foods,no obvious incentives,strenuous exercise,polluted weather;compared with asthma group and control group,the number of positive respiratory symptoms and signs in asthma group Compared with the control group,the eosinophil count,IL-4 level,and Ig-E level were significantly higher than those of the control group.The C-ACT score and pulmonary function parameters were significantly lower than those of the control group,and the gaps were statistically significant.(P?0.05)the number of positive respiratory symptoms and signs,eosinophil count,IIL-4 level and Ig-E level in asthma group after hypothermia and high air pressure were significantly higher than those in the group,-ACT score and pulmonary function parameters were significantly lower than those at the time of enrollment,and the differences were statistically significant(P?0.05);there was no statistical significance in the comparison of all indicators of the asthma group after polluted weather and thetime of enrollment,(P?0.05);there was no significant difference between the control group and the heavy pollution group and the low temperature and high pressure group,(P?0.05).Conclusions: ?Upper respiratory tract infections are the leading cause of acute asthma attacks in children.In addition,irritating food,strenuous exercise,and weather changes also contribute to the acute attacks of asthma in some children.Avoiding or controlling these factors has a positive effect on preventing or exacerbating asthma;?Low-pressure high-pressure weather increases the risk of asthma attacks.Pay attention to the weather and keep warm in real time.In haze weather,reasonable protection can effectively reduce the acute attack of asthma;?The following manifestations may increase the possibility of asthma diagnosis: personal allergies,family allergies and / or asthma history,eating irritating food,respiratory symptoms after strenuous exercise and weather changes,peripheral blood eosinophil count,IL-4and Ig-E levels are high;?Pulmonary function combined with peripheral blood eosinophil count,IL-4 and Ig-E examination can improve the accuracy of assessment of asthma control period,predict the risk of asthma occurrence and onset,and adjust the dosage and treatment period of asthma control period.