Correlation Of RDW,PDW And The Degree Of Coronary Artery Lesion In Acute STEMI Patients

Purpose:To investigate the correlation between red blood cell distribution width(RDW),platelet distribution width(PDW)and the degree of coronary artery lesion in patients with acute STEMI.Method:Who was selected to be diagnosed as coronary atherosclerotic heart disease-acute ST-elevation myocardial infarction at the Cardiovascular Diseases Medical Center of the First Hospital of Jilin University from July 2016 to June 2017.Patients who received emergency percutaneous coronary intervention(PCI)were divided into coronary single-vessel disease group and multiple-vessel disease group according to the results of coronary angiography.The modified Gensini score was used to quantitatively evaluate the degree of coronary artery disease.: Coronary moderate to severe stenosis group(improved Gensini score> 7),mild coronary stenosis group(improved Gensini score ≤ 7),retrospective clinical data,laboratory blood biochemical indicators,color Doppler ultrasound,electrocardiogram,etc.of patients in each group Examination results,using multi-factor Logistic regression model to analyze the factors affecting the degree of coronary artery disease in STEMI patients.Result:1.Compared with the single-vessel disease group: the multi-vessel disease group had a higher age(P <0.001),with an average age of 60 ± 10 years;the multiple-vessel disease group had a higher proportion of hypertension history,diabetes history,and ischemic stroke history.High(P <0.05);the level of albumin(ALB)in the multi-vessel disease group was low,and the red blood cell distribution width(RDW)and fasting blood glucose(FBG)levels in the multi-vessel disease group were high,with statistically significant differences(P < 0.05).2.Logistic multi-factor regression to screen for risk factors for multi-vessel disease: the patient’s previous history of hypertension,red blood cell distribution width(RDW),low-density lipoprotein cholesterol(LDL-C)are independent risk factors for multi-vessel disease,and albumin(ALB)is Protective factors for multi-vessel disease.3.Compared with the mild stenosis group: the moderate to severe stenosis group is older,with an average age of 60(52,66)years(P <0.05);the moderate to severe stenosis group has more women(P <0.05);moderate to severe The proportion of history of hypertension and ischemic stroke in the stenosis group was higher(P <0.05);the red blood cells(RBC)in the moderate to severe stenosis group were smaller(P <0.05);the platelet distribution width(PDW)in the moderate to severe stenosis group The fasting blood glucose(FBG)level was higher,and the difference was statistically significant(P <0.05).4.Logistic multivariate regression screened the risk factors of the improved Gensini score: the patient’s previous history of hypertension,history of ischemic stroke,platelet distribution width(PDW),and fasting blood glucose(FBG)were independent risk factors for improving the high score of the improved Gensini score.Conclusion:1.In STEMI patients,the higher the RDW level and the lower the ALB level,the greater the number of coronary lesions.RDW is an independent risk factor for coronary multi-vessel disease,and ALB is a protective factor for coronary multi-vessel disease.2.In patients with STEMI,the higher the PDW and FBG levels,the higher the modified Gensini score,and the more severe the coronary artery disease.PDW and FBG are independent risk factors for the high score of the modified Gensini score.