Investigation On Prevalence Of Helicobacter Pylori Infection And Influence Factors In Baoshan District Of Shanghai In Examination Population

Background & Objectives Helicobacter pylori(H.pylori)is closely related to the occurrence of chronic gastritis,peptic ulcer,gastric mucosa-associated lymphoma,gastric cancer and other diseases,and poses a serious threat to human health.It has drawn more and more attention of clinicians.To investigate the status of Helicobacter pylori infection in Baoshan district area of Shanghai and analyze the influencing factors,so as to provide reference for the prevention of H.pylori infection and important value for early prevention and treatment of H.pylori-related diseases.Methods 1.The residents in Baoshan district who underwent routine physical examination were enrolled in the physical examination center of Shanghai Ninth People's Hospital(the North Branch),Shanghai Jiaotong University School of Medicine from January 1th 2017 to January 1th 2018.The results of [13C] urea breath test were used to study the status of H.pylori infection and its relationship with gender,age and occupation.2.For patients who taken the [13C] urea breath test in the Clinic of Shanghai Ninth People's Hospital(the North Branch),Shanghai Jiaotong University School of Medicine with non-specific gastrointestinal symptom,the questionnaires prepared by our department were used to further understand the related factors of H.pylori infection.Results 1.A total of 5164 people were involved,and H.pylori infection was 36.35% in general.Occupations are related to the detection rate of H.pylori(P<0.05).The H.pylori infection rate of Steel workers was the highest at 41.77%.There was no significant correlation between gender and age with H.pylori infection rate(P>0.05).2.746 of the 800 patients completed all items were included in the influence factor analysis.The detection rate of H.pylori was significantly higher(P<0.05)among married,drinking,eating out,smoked food,high-salt,high-fat diet,and family history of H.pylori infection.There was no association between H.pylori infection with BMI,smoking,stay up,pets,sweets,honey,curry,vinegar,spicy food,soy products,regular diet,breakfast,midnight snack,and general non-gastrointestinal tract chronic disease history(including hypertension,diabetes,coronary heart disease)(P>0.05).Conclusions 1.The H.pylori infection rate of health examination population in Baoshan area is lower than the national average.2.Occupations,married,drinking alcohol,eating out often,eating smoked food,high-salt high-fat diet,and family history of H.pylori infection are influencing factors of H.pylori infection.3.There was no association between H.pylori infection with gender,age,BMI,smoking,stay up,pets,sweets,honey,curry,vinegar,spicy food,soy products,regular diet,breakfast,midnight snack,and some chronic diseases such as hypertension,diabetes,coronary heart disease.