Clinical Observation Of Kunning Anshen Decoction In Treating Perimenopausal Insomnia Of Kidney Yin Deficiency Type

Objective: In this study,through the clinical observation of Kunning Anshen Decoction in the treatment of perimenopausal insomnia with kidney-yin deficiency,the changes in sleep time and sleep quality were recorded to evaluate the efficacy of Kunning Anshenyin Decoction.Methods: Sixty patients who met the inclusion criteria of kidney-yin deficiency type perimenopausal insomnia were divided into two groups using random number table method,30 cases in each group.The observation group was treated with Kunning Anshen Decoction and the control group was treated with Kuntai capsules for 4 weeks.The two groups filled out the TCM syndrome score scale,the Pittsburgh Sleep Quality Index(PSQI)scale,and the modified Kupperman score scale before treatment,after treatment,and during follow-up,analyzed the changes in each score,and compared the differences.Results:1.Comparison of total effective rate: The total effective rate of the observation group was 93.10%,and the total effective rate of the control group was 78.57%.The observation group was better than the control group,and the difference was statistically significant(P<0.05).2.Comparison of the efficacy of TCM syndromes between the two groups: after treatment and during follow-up,the comparison between the groups and within the group was performed,and the difference was statistically significant in the total score of TCM syndromes and some individual symptoms(P<0.05);comparison of forgetfulness only,the difference was not statistically significant(P>0.05).It shows that both groups can improve the symptoms of restless sleep,sore waist and knees,five upset fever,hot flashes,sweating and other symptoms.They are durable and the observation group has better efficacy than the control group.3.PSQI scale score comparison between the two groups: after treatment and during follow-up,within the group comparison,the two groupscompared the total PSQI score and each sub-item with before treatment,the difference was statistically significant(P<0.05).The comparison between the groups,only in the comparison of hypnotic drugs and day dysfunction,the difference was not statistically significant(P>0.05).It shows that both groups can significantly improve various evaluation indexes of sleep,and the curative effect is stable,but the curative effect of the observation group is more significant.4.Modified Kupperman scale score comparison between the two groups:after treatment and during follow-up,the Kupperman score was compared between and within the group,and the differences were statistically significant(P<0.05).It shows that both groups can effectively improve the symptoms related to perimenopause,and they are persistent,while the observation group can better relieve the symptoms.Conclusion:1.Kunning Anshen Decoction has significant clinical efficacy in treating perimenopausal insomnia with kidney-yin deficiency type,and has the characteristics of high total effective rate.2.While improving sleep,Kunning Anshen Decoction also has a therapeutic effect on other clinical symptoms associated with perimenopausal women with kidney-yin deficiency type,such as soft waists and knees,five upsets,hot flashes,sweating,dry mouth,and palpitations,thus improving the quality of life of patients.3.Kunning Anshen Decoction is an effective prescription for treating perimenopausal insomnia of kidney-yin deficiency type.It has high safety,few side effects,and no obvious adverse reactions.It is worthy of popularization and clinical use.