Meta-analysis On The Curative Effect Of Traditional Chinese Medicine In The Treatment Of Simole Obesity

Objective : Using the method of systematic review and Meta-analysis of evidence-based medicine(EBM)to evaluate the effectiveness and safety of traditional Chinese Medicine(TCM)in the treatment of simple obesity,to provide evidence-based evidence for the effectiveness of Chinese Medicine Treatment of simple obesity,at the same time for clinical treatment of simple obesity to provide new ideas.Methods:Using the computer to search the related literatures on the treatment of simple obesity with Chinese herbal medicine published in various large databases at home and abroad,and after summing up and sorting out the retrieved literatures,cochrane risk bias assessment tool was used to evaluate the quality of the selected literature and Revman5.30 software was used to analyze the original data.Results:The study included 11 papers published in the past 15 years on the treatment of simple obesity,of which 8 Randomized controlled trial papers,3 journal Papers.There were 758 cases of simple obesity,377 cases in treatment group and 381 cases in control group.Intervention measures included Chinese herbal decoction,Chinese patent medicine and medicated diet.The quality of the study was acceptable,of which 3 were of high quality.The outcome measures included total efficiency?body weight?body mass index?waist circumference?hip circumference?waist to hip ratio?total cholesterol?triglycerides ?low-density lipoprotein?high-density lipoprotein?leptin and fasting blood glucose.The results were analyzed by Revman 5.30 software in a Meta-analysis.The 11 studies included were divided into 5 subgroups according to the course of treatment.The results of a Meta-analysis showed that at 4 weeks of treatment,the total effective rate,BMI reduction,waist circumference reduction,total cholesterol and triglyceride reduction,and Low-density lipoprotein improvement of TCM were better than those of that of non-traditional Chinese medicine therapy,but it was not significant in terms of weight loss or high-density Lipoprotein.Over the course of 8 weeks,Chinese medicine was superior to non Chinese medicine in terms of total response rate,weight loss,BMI reduction,waist circumference,total cholesterol and triglyceride,and Leptin improvement,however,there was nosignificant improvement in hip circumference and waist to hip ratio,Low-density Lipoprotein and high-density Lipoprotein,and fasting blood glucose.At 12 weeks,Chinese medicine was superior to non-Chinese medicine in total effective rate,weight loss,reduction of BMI?WC?HC?WHR,improvement of blood lipids and FBG was significantly lower.Since only one study was included in the 24-week group,only a descriptive analysis was performed.Conclusions:1.The Clinical Curative effect of Chinese Medicine Decoction,Chinese Patent Medicine and Chinese Medicine Diet on simple obesity is exact and better than diet exercise alone.2.Chinese Medicine Decoction,Chinese Patent Medicine,Chinese Medicine Diet Treatment of simple obesity has a high safety,fewer side effects.3.Chinese medicine for obesity caused by fatigue,heavy limbs,loose stools and other symptoms have a certain degree of relief.4.This study found that the Chinese Medicine Treatment of simple obesity of general quality and mostly small sample RCT,but further large sample,high-quality studies to provide more reliable evidence-based.