Study On The Influencing Factors Of Short-Time TIA Progressing To Cerebral Infarction

ObjectiveIn this study,convenient sampling was used to evaluate the incidence of TIA short-term progression to cerebral infarction by combining clinical objective examination indexes with subjective scale,and the influencing factors were comprehensively analyzed to clarify the risk factors and protective factors,so as to provide theoretical basis and evidence support for the individualized secondary prevention of TIA patients.MethodsIn this study,during the peroid from November 2018 to October 2019,the nested case control study method was adopted to investigate the patients who were diagnosed with TIA and were hospitalized for more than 1 week in two comprehensive Third Grade Class-A hospitals in a city of Henan Province.The questionnaire included general demographic data,clinical risk factors,health promoting lifestyle profile II scale,and evaluated the influencing factors of short-term TIA patients processing to cerebral infarction through the method of combining objective data and subjective scale.Using Epidata3.1 to establish the database,using SPSS22.0 software for statistical analysis,with P<0.05 as the statistical differences.Descriptive analysis used mean ?standard deviation(?? ?s);Single factor analysis methods such as two independent sample t-test ??2 test and rank sum test were used for group comparison,and multivariate analysis used binary logistic regression analysis.Results1.General information status of subjectsA total of 231 patients with TIA were included in this study,aged between 30 and 88 years,with an average age of 61.0?10.9 years,including 137 males(59.3%)and 94 females(40.7%).most of the TIA patients were married(71.0%),with a junior high school education level and below(41.1%),with a family per capita income more than 3000 yuan(57.6%).The objectives had no diabetes,hypertension,coronary heart disease and family history,their proportions were 55.0%,57.6%,70.2%.and 65.8%,and 51.9%;and70.6% and 75.3% of the objectives did not smoke or drink.The clinical manifestations of TIA are mostly speech disorders without limb weakness(43.7%),the probability of remission within 1 hour is relatively high(43.7%).2.ABCD2 scores of the subjectsNearly half of the patients(48.1%)were in the low-risk range of ABCD2 scale after the comprehensive scoring of age,blood pressure,TIA clinical manifestations,TIA duration and diabetes.3.Healthy behaviors level of the subjectsThe healthy behaviors of the subjects were at a middle and low level,with a score of 93.01?11.41.Compared with the Health promoting lifestyle profile II scores,the daily healthy behaviors of the subjects ranged between "never" and "sometimes".The single item in the six dimensions of healthy behavior showed that the higher scores were nutrition(1.89?0.48)and health responsibility(1.80?0.50).the lower scores were exercise,stress and self realization(1.79? 0.46,1.77 ?0.39,1.68 ? 0.43).4.Incidence of TIA short-term progressing to cerebral infarctionThis study takes one week as the observation node to check whether there is responsible infarct or not,according to the MRI examination: 168 subjects did not progress to cerebral infarction,63 subjects progressed to cerebral infarction,231 subjects processed to cerebral infarction 1 week after first onset.5.Single factor analysis of TIA short-term progression to cerebral infarctionThere were different degrees of statistical differences in sex,age,BMI,education level,family income,hypertension,diabetes mellitus,coronary heart disease,family history,TIA clinical manifestation,TIA duration,carotid plaque,LDL-C,TC,ABCD2 scores,interpersonal relationship,health responsibility,stress response and exercise between TIA group and cerebral infarction group(P< 0.05).6.Binary logistic regression analysis of TIA short-term progressing to cerebral infarctionThe results of binary logistic regression showed that family history,ABCD2 score,BMI,education level,interpersonal relationship,health responsibility and exercise were independent factors of TIA short-term progression to cerebral infarction(P < 0.05).Conclusions1.The incidence rate of cerebral infarction was 27.2% for the short-term TIA progression.The risk assessment and prevention and treatment of the short-term TIA progression for cerebral infarction need to be attached great importance in clinical practice.2.Family history,obesity and high-risk group score in ABCD2 were independent risk factors for TIA short-term progressing to cerebral infarction.3.College degree or above,better interpersonal relationship,higher health responsibility and better exercise are the protective factors of TIA short-term progressing to cerebral infarction.